Page 100 - JCTR-11-2

Journal of Clinical and

Translational Research

MEDICAL HYPOTHESIS
A systematic review protocol of medical and

clinical research landscapes and quality in
Malaysia and Indonesia (REALQUAMI)

Boon-How Chew * , Shaun Wen Huey Lee 2 , Lim Poh Ying 3 ,
1
Soo Huat Teoh 4 , Aneesa Abdul Rashid 1 , Navin Kumar Devaraj 1 ,
Adibah Hanim Ismail 1 , Abdul Hadi Abdul Manap 1 ,
Fadzilah Mohamad 1 , Aaron Fernandez 5 , Hanifatiyah Ali 1 ,
Puteri Shanaz Jahn Kassim 1 , Nurainul Hana Shamsuddin 1 ,
Noraina Muhamad Zakuan 6 , Akiza Roswati Abdullah , and
7
Indah S. Widyahening 8
1 Department of Family Medicine, Faculty of Medicine and Health Science, Universiti Putra Malaysia,
Serdang, Selangor, Malaysia
2 School of Pharmacy, Monash University Malaysia, Bandar Sunway, Selangor, Malaysia
3 Department of Community Health, Faculty of Medicine and Health Science, Universiti Putra
Malaysia, Serdang, Selangor, Malaysia
4 Advanced Medical and Dental Institute (AMDI), Universiti Sains Malaysia, Kepala Batas, Penang,
Malaysia
5 Department of Psychiatry, Faculty of Medicine and Health Science, Universiti Putra Malaysia,
*Corresponding author: Serdang, Selangor, Malaysia
Boon-How Chew 6 Department of Biomedical Sciences, Faculty of Medicine and Health Science, Universiti Putra
(chewboonhow@upm.edu.my) Malaysia, Serdang, Selangor, Malaysia
Citation: Chew B, Lee SWH, 7 Medical and Health Sciences Library, Faculty of Medicine and Health Science, Universiti Putra
Ying LP, et al. A systematic Malaysia, Serdang, Selangor, Malaysia
review protocol of medical and 8 Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia
clinical research landscapes and
quality in Malaysia and Indonesia
(REALQUAMI). J Clin Transl Res.
2025;11(2):94-105.
doi: 10.36922/jctr.24.00071
Abstract
Received: October 22, 2024
Background: The evolving landscape of clinical and biomedical research has raised
1st Revised: December 11, 2024 concerns about waste and quality. Poorly conducted studies mislead clinical practice
2nd Revised: December 12, 2024 and compromise patient outcomes. Reliable data from past research are essential
Accepted: March 11, 2025 for research quality improvement. Aim: The aim of the study was to characterize
and assess the quality of research in Malaysia and Indonesia. Methods: To establish
Published online: April 4, 2025 the proposed systematic review protocol, we will search PubMed, Cochrane Library,
Copyright: © 2025 Author(s). CINAHL, and PsycINFO for studies published from 1962 to 2019, supplemented
This is an open-access article by MyMedR for Malaysian research. Two reviewers will independently screen
distributed under the terms of the
Creative Commons AttributionNon- studies, extract data, and assess quality. Phase 1 will descriptively report research
Commercial 4.0 International (CC characteristics, including researcher profiles and journal outlets. In Phase 2, a quality
BY-NC 4.0), which permits all screening tool will be validated across three domains: relevance, methodological
non-commercial use, distribution,
and reproduction in any medium, credibility, and result usefulness. Associations between research characteristics
provided the original work is and quality will be analyzed through multivariable regression and longitudinal
properly cited. trends will be explored. Results: Findings from the proposed systematic review
Publisher’s Note: AccScience protocol will generate baseline data for national and international comparisons,
Publishing remains neutral with guiding stakeholders, researchers, funders, and policymakers on research evolution
regard to jurisdictional claims in
published maps and institutional and quality trends. Results may inform improvement initiatives and resource
affiliations. allocation for understudied areas. Conclusion: This review aims to establish a

Volume 11 Issue 2 (2025) 94 doi: 10.36922/jctr.24.00071