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Figure 4. Mapping neurodevelopmental disorders: Genetic causes → Organoid research outcomes
Abbreviations: EEG: Electroencephalography; fMRI: Functional magnetic resonance imaging; RNA-seq: RNA sequencing.
In the context of personalized medicine, integrating robust computational tools to analyze multidimensional
patient-derived organoid data with clinical phenotypes datasets. Ethical concerns related to the generation and
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remains a substantial challenge. High-throughput screening manipulation of human brain-like tissues also demand
of therapeutic compounds in organoids is still in its infancy ongoing discussion and regulation, particularly as these
and faces issues such as scalability, cost, and the need for models gain complexity. 263
Volume 1 Issue 3 (2025) 16 doi: 10.36922/OR025100010
