Page 49 - OR-1-3

77. Sloan SA, Andersen J, Pasca AM, Birey F, Pasca SP. and for drug screening. Stem Cells Int. 2022;2022:2150680.
Generation and assembly of human brain region- doi: 10.1155/2022/2150680
specific three-dimensional cultures. Nat Protoc.
2018;13(9):2062-2085. 89. Ranzoni AM, Tangherloni A, Berest I, et al. Integrative
single-cell RNA-Seq and ATAC-Seq analysis of
doi: 10.1038/s41596-018-0032-7
human developmental hematopoiesis. Cell Stem Cell.
78. Tamada A, Muguruma K. Recapitulation and investigation 2021;28(3):472-487.e7.
of human brain development with neural organoids. IBRO
Neurosci Rep. 2024;16:106-117. doi: 10.1016/j.stem.2020.11.015
90. Rajan A, Fame RM. Brain development and bioenergetic
doi: 10.1016/j.ibneur.2023.12.006
changes. Neurobiol Dis. 2024;199:106550.
79. Del Dosso A, Urenda JP, Nguyen T, Quadrato G. Upgrading
the physiological relevance of human brain organoids. doi: 10.1016/j.nbd.2024.106550
Neuron. 2020;107(6):1014-1028. 91. Tang F, Lao K, Surani MA. Development and applications
doi: 10.1016/j.neuron.2020.08.029 of single-cell transcriptome analysis. Nat Methods.
2011;8(4 Suppl):S6-S11.
80. Susaimanickam PJ, Kiral FR, Park IH. Region specific brain
organoids to study neurodevelopmental disorders. Int J Stem doi: 10.1038/nmeth.1557
Cells. 2022;15(1):26-40. 92. Satam H, Joshi K, Mangrolia U, et al. Next-generation
doi: 10.15283/ijsc22006 sequencing technology: Current trends and advancements.
Biology (Basel). 2023;12(7):997.
81. Yakoub AM. Cerebral organoids exhibit mature neurons and
astrocytes and recapitulate electrophysiological activity of doi: 10.3390/biology12070997
the human brain. Neural Regen Res. 2019;14(5):757-761. 93. Pavon N, Diep K, Yang F, et al. Patterning ganglionic
doi: 10.4103/1673-5374.249283 eminences in developing human brain organoids using a
morphogen-gradient-inducing device. Cell Rep Methods.
82. Park S, Min CH, Choi E, et al. Long-term tracking of neural 2024;4(1):100689.
and oligodendroglial development in large-scale human
cerebral organoids by noninvasive volumetric imaging. Sci doi: 10.1016/j.crmeth.2023.100689
Rep. 2025;15(1):2536. 94. Trujillo CA, Gao R, Negraes PD, et al. Complex oscillatory
doi: 10.1038/s41598-025-85455-8 waves emerging from cortical organoids model early
human brain network development. Cell Stem Cell.
83. Marton RM, Miura Y, Sloan SA, et al. Differentiation and 2019;25(4):558-569.e7.
maturation of oligodendrocytes in human three-dimensional
neural cultures. Nat Neurosci. Mar 2019;22(3):484-491. doi: 10.1016/j.stem.2019.08.002
doi: 10.1038/s41593-018-0316-9 95. Quadrato G, Nguyen T, Macosko EZ, et al. Cell diversity and
network dynamics in photosensitive human brain organoids.
84. Al-Mhanawi B, Marti MB, Morrison SD, et al. Protocol for Nature. 2017;545(7652):48-53.
generating embedding-free brain organoids enriched with
oligodendrocytes. STAR Protoc. 2023;4(4):102725. doi: 10.1038/nature22047
doi: 10.1016/j.xpro.2023.102725 96. Kiaee K, Jodat YA, Bassous NJ, Matharu N, Shin SR.
Transcriptomic mapping of neural diversity, differentiation
85. Shim G, Romero-Morales AI, Sripathy SR, Maher BJ. and functional trajectory in iPSC-derived 3D brain organoid
Utilizing hiPSC-derived oligodendrocytes to study myelin models. Cells. 2021;10(12):3422.
pathophysiology in neuropsychiatric and neurodegenerative
disorders. Front Cell Neurosci. 2023;17:1322813. doi: 10.3390/cells10123422
doi: 10.3389/fncel.2023.1322813 97. Ilieva MS. Non-Coding RNAs in neurological and
neuropsychiatric disorders: Unraveling the hidden players in
86. Mehl LC, Manjally AV, Bouadi O, Gibson EM, Tay TL. disease pathogenesis. Cells. 2024;13(12):1063.
Microglia in brain development and regeneration.
Development. 2022;149(8):dev200425. doi: 10.3390/cells13121063
doi: 10.1242/dev.200425 98. Andrews MG, Kriegstein AR. Challenges of organoid
research. Annu Rev Neurosci. 2022;45:23-39.
87. Zhang W, Jiang J, Xu Z, et al. Microglia-containing human
brain organoids for the study of brain development and doi: 10.1146/annurev-neuro-111020-090812
pathology. Mol Psychiatry. 2023;28(1):96-107. 99. Anaparthy N, Ho YJ, Martelotto L, Hammell M, Hicks J.
doi: 10.1038/s41380-022-01892-1 Single-cell applications of next-generation sequencing. Cold
Spring Harb Perspect Med. 2019;9(10):a026898.
88. Ma C, Seong H, Li X, Yu X, Xu S, Li Y. Human brain organoid:
A versatile tool for modeling neurodegeneration diseases doi: 10.1101/cshperspect.a026898

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