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Figure 5
Figure 5: Therapeutic Applications of 3D-Printed Microfluidics in Oncology. (A)
The fabrication of microfluidic devices and their application in formulating various
nanodelivery systems: nanospheres, liposomes, nanocrystals, quantum dots, and solid
lipid nanoparticles, enhance the efficacy and homogeneity of nanomedicines for tumor
therapy. Adapted with permission from ref.[99] Copyright © 2025 American Chemical
Society. (B) Microfluidics-fabricated small-sized (with a kinetic diameter of
approximately 80 to 150 nm), tumor-penetrable, endosome-escaping, and
bioresponsive hyaluronic acid nanogels (HA-NGs) were developed for CD44-targeted
intracellular delivery of therapeutic proteins. Adapted with permission from ref.[103]
Copyright © 2019 American Chemical Society. (C) PTX-SLNs were produced using
microfluidic technology by mixing an aqueous surfactant solution with lipids and drug
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