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Figure 7
Figure 7: Separation of Circulating Tumor Biomarkers Using 3D Printing
Microfluidic Technology. (A) Theoretical device design for analysis of CTCs and
circulating proteins and DNA from whole blood. Whole blood is perfused through a
series of microchambers and microchannels that leverage several microscale-based
separation techniques to isolate multiple components such as immune cells, CTCs,
ctDNA, proteins, and exosomes. Adapted with permission from ref.[127] (B) Clinical
microfluidic devices have revolutionized noninvasive liquid biopsy for ctDNA
detection and analysis by enabling rapid, cost-effective, and simple workflows that
allow repeatable molecular analysis anytime and anywhere. Adapted with permission
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