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Artificial Intelligence in Health                                 Robotics and Vivaldi AI for ALS assessment



            et al.  outlined how such robotic systems can be useful   Milan. Participants met the diagnostic criteria for probable
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            for the management infectious diseases, including disease   or definite ALS as outlined in the revised El Escorial
            prevention and monitoring, clinical care, laboratory   criteria.   Inclusion  criteria  required  ALS  patients  to
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            automation, and logistics, during the COVID-19     exhibit a minimum ALSFRS-R score of ≥2 points in both
            pandemic. However, challenges such as difficult operation,   speech and handwriting questions, with a total ALSFRS-R
            maintenance, reliability, and high costs hinder their   score of ≥18 points. In addition, all participants were
            widespread adoption in private homes.              capable of verbal communication to answer interview
              Despite these challenges, numerous research efforts have   questions. Patients displaying severe cognitive and
            successfully tested assistive robotics in real-world settings,   behavioral impairment, as determined by the Edinburgh
            demonstrating their acceptance and usability in personalized   Cognitive Assessment Scale at enrollment, were excluded
            daily assistive plans.  This progress highlights the potential   from the study. Before participation, all patients provided
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            for  these  technologies  to  become  integral  components  of   informed consent, which was approved by the Local Ethics
            patient care, improving the overall management and quality   Committee, Grande Ospedale Metropolitano Niguarda,
            of life for individuals with neurological disorders. 21  Milano, Italy (Protocol Number: 404-092019).
              For instance, Ghafurian  et al.  examined the use of   4.2. Vivaldi AI system
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            social robots for dementia care, highlighting various   Sanbot Elf is enhanced by the cutting-edge Vivaldi AI
            levels of robot autonomy and assistive objectives such   system, which equips it with advanced capabilities such as
            as connecting patients with distant family members,   speech recognition, facial expression analysis, and gesture
            providing companionship, promoting health, and aiding   understanding. Unlike conventional setups reliant on
            in daily tasks. The authors underscored the need for   remote cloud servers, this AI engine processes data locally
            robots to be easy to use and maintain, and reliable, as   on the robot itself, facilitating faster response times and
            these factors significantly impact their adoption in private   potentially reducing operational costs by minimizing data
            homes.  Saunders  et al.   reported  the  use  of  the  Care-  transfers. With Vivaldi AI at its core, Sanbot Elf adeptly
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            O-Bot 3 for complex interactions with elderly people,   comprehends  human  communication,  enabling  it  to
            facilitating independent living and daily tasks. Schroeter   engage with users in a natural and intelligent manner. Key
            et al.  reported the usability of the social assistive robot,   functionalities include: (1) speech recognition, facilitating
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            which provides questionnaires and cognitive stimulation   effortless voice interaction with users; (2) natural language
            games to monitor cognitive decline to be used in a home   processing, enabling the robot to understand and respond
            setting. Instead, Fischinger et al.  developed a care robot   to human language nuances; (3) facial expression
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            (namely Hobbit robot prototype) for aging by means of   analysis,  allowing  Sanbot  Elf  to  discern  user  sentiment
            fall prevention/detection. The Hobbit project combined   by interpreting facial cues, thereby tailoring its responses
            research from robotics, gerontology, and human-robot   accordingly; (4) gesture understanding, enhancing the
            interaction to develop a care robot, which is capable of fall   fluidity of communication between the robot and users;
            prevention and detection as well as emergency detection   and (5) seamless communication, ensuring smooth and
            and handling. Moreover, to enable daily interaction with   intuitive interaction between Sanbot Elf and its human
            the robot, other functions were added, such as bringing   counterparts.
            objects, offering reminders, and entertaining. Casey
            et al.  have demonstrated that robots could promote social   4.3. Robotic administration of ALSFRS-R
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            connection and reduce loneliness among dementia patients   questionnaire
            in a long-term residential setting. Finally, Neerincx et al.
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            designed a personalized assistive robot for patients with   For this study, the Sanbot Elf unit is equipped to administer
            cognitive impairments,  taking  into account their  daily   the  ALSFRS-R  questionnaire  using  a structured  format
            needs and characteristics such as their personal cognitive,   allowing patients to answer questions with either “yes” or
            emotional, and psychological status as well as their   “no.” This approach is intentionally adopted to minimize
            cultural background, which are not always easily modeled   ambiguity in patient responses. Patients have the option
            according to well-defined classifications.         to respond either verbally or by utilizing the touchscreen
                                                               display, particularly beneficial for those experiencing
            4. Data and methods                                dysarthria or hypophonia. The Vivaldi AI system guides
                                                               patients through the ALSFRS-R questionnaire, dynamically
            4.1. Participants                                  adjusting the sequence of questions based on the patient’s
            This study enrolled a cohort of 28 ALS patients who   responses. This ensures a personalized experience tailored
            underwent evaluation at the Nemo Clinical Center in   to each individual’s needs. Throughout the questionnaire,


            Volume 1 Issue 4 (2024)                         76                               doi: 10.36922/aih.3732
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