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Advances in Radiotherapy
& Nuclear Medicine NCRT for T3N0M0 ESCC
A B
C D
E F
Figure 3. Kaplan–Meier curves for survival analysis in the study cohort and subgroup. (A) Overall survival across the entire population. (B) Disease-free
survival across the entire population. (C) Overall survival in the matched sample. (D) Disease-free survival in the matched sample. (E) Overall survival in
the subgroup. (F) Disease-free survival in the subgroup.
Abbreviations: NCRT+S: Neoadjuvant chemoradiotherapy plus surgery; pCR: Pathologically complete response.
regarding DFS (P = 0.987, Figure 3F). Within the NCRT + number of LNs excised, and a COX subgroup analysis
S group, neither the pCR nor the non-pCR groups showed was performed. The results showed that in the overall
any benefits regarding OS (P = 0.73, Figure 3E) or DFS population, patients aged ≤65 years, male patients, those
(P = 0.17, Figure 3F). with KPS of 80, without weight loss, with tumor length
Subgroups were also created based on age, gender, ≤5 cm, without LVI, without PNI, and with fewer than
KPS, presence of weight loss, tumor location, tumor 18 LNs excised significantly benefited from NCRT + S
length, presence of LVI, presence of PNI, and the (all P < 0.05). Patients with LVI who underwent NCRT
Volume 2 Issue 3 (2024) 6 doi: 10.36922/arnm.3821
