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Funding 2023;23(1):588.
This work was supported by the National Natural Science doi: 10.1186/s12885-023-11089-6
Foundation of China (Grant Nos. 82102173, 82072094, and 3. Tan LT, Tanderup K, Kirisits C, et al. Image-guided adaptive
12275162), the Natural Science Foundation of Shandong radiotherapy in cervical cancer. Semin Radiat Oncol.
Province (Grant No. ZR2019LZL017), the Precision 2019;29(3):284-298.
Radiotherapy Submit plan 2021HZ81, the Taishan Scholars
Project of Shandong Province (Grant No. ts201712098), doi: 10.1016/j.semradonc.2019.02.010
and the Shandong Medical Association Clinical Research 4. Winkel D, Bol GH, Kroon PS, et al. Adaptive radiotherapy:
Fund – Qilu Special Project (YXH2022ZX02198). The Elekta Unity MR-linac concept. Clin Transl Radiat
Oncol. 2019;18:54-59.
Conflict of interest doi: 10.1016/j.ctro.2019.04.001
The authors declare that they have no competing interests. 5. Eminowicz G, Rompokos V, Stacey C, Hall L, McCormack M.
Understanding the impact of pelvic organ motion on dose
Author contributions delivered to target volumes during IMRT for cervical cancer.
Conceptualization: Yong Yin, Zhenjiang Li Radiother Oncol. 2017;122(1):116-121.
Formal analysis: Kaiwen Zhou doi: 10.1016/j.radonc.2016.10.018
Investigation: Kaiwen Zhou, Jinhu Chen, Junfeng Zhao, 6. Chen J, Liu P, Chen W, et al. Early changes of volume and
Xingwei An spatial location in target and normal tissues caused by IMRT
Methodology: Junfeng Zhao, Xingwei An for cervical cancer. Tumori. 2016;102(6):610-613.
Writing – original draft: Kaiwen Zhou, Jinhu Chen doi: 10.5301/tj.5000413
Writing – review & editing: Kaiwen Zhou, Jinhu Chen,
Yong Yin, Zhenjiang Li 7. Yan D, Vicini F, Wong J, Martinez A. Adaptive radiation
therapy. Phys Med Biol. 1997;42(1):123-132.
Ethics approval and consent to participate doi: 10.1088/0031-9155/42/1/008
The study was approved by the Ethical Review Committee 8. Hunt A, Hansen VN, Oelfke U, Nill S, Hafeez S. Adaptive
of Shandong Cancer Hospital (ethics approval code: radiotherapy enabled by MRI guidance. Clin Oncol (R Coll
SDTHEC2024007028; approval date: July 22, 2024). Radiol). 2018;30(11):711-719.
Consent for publication doi: 10.1016/j.clon.2018.08.001
9. Yan D, Wong J, Vicini F, et al. Adaptive modification of
All participants were adequately informed about the treatment planning to minimize the deleterious effects
study procedures, risks, and benefits and they agreed of treatment setup errors. Int J Radiat Oncol Biol Phys.
to participate in this study voluntarily. In addition, we 1997;38(1):197-206.
obtained permission from all participants regarding doi: 10.1016/s0360-3016(97)00229-0
the publication of study results, which is reflected in the
consent documentation. 10. Yan D, Lockman D, Brabbins D, Tyburski L, Martinez A. An
offline strategy for constructing a patient-specific planning
Availability of data target volume in adaptive treatment process for prostate
cancer. Int J Radiat Oncol Biol Phys. 2000;48(1):289-302.
The datasets generated and analyzed during the current
study are available from the corresponding author upon doi: 10.1016/s0360-3016(00)00608-8
reasonable request. 11. Han EY, Wang H, Briere TM, et al. Brain stereotactic
radiosurgery using MR-guided online adaptive planning for
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Volume 2 Issue 4 (2024) 8 doi: 10.36922/arnm.4919

