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Global Health Econ Sustain                                         Stochastic modeling of age at menopausal



            of menopause using data from Nepalese women. Among              1
            several  distributions,  they  used  the  type-I  extreme  value   Fx () =    x−             (2)
                                                                   1
                                                                               γ
            model to describe the distribution of the menopausal timing    −   β   
            of Nepalese women. By observing the right skew nature of    1+ e
            data, normal, Weibull, logistic, and log-logistic distributions   Where γ > 0 is any arbitrary threshold parameter and
            have been used in this paper to describe the distributional   β > 0 represents the scale factor of the model. The mean
            pattern of Nepali women. Logistic distribution was found   and variance of the distribution were computed using the
            to better capture the distributional pattern in this study.      βπ
                                                                              22
            Furthermore, a new four-parameter RGLLog distribution was   relation as γ and   , respectively (Johnson et al., 1995).
            tested for the goodness of fit. This distribution was applied     3
            since it has four parameters and the result may create a more   3.2.2. Log-logistic distribution
            realistic menopause prediction pattern.
                                                               If x denotes the age at menopause of women, the PDF and
            3. Methods and models                              the CDF that follow the log-logistic (LLog) distribution
            In this article, we used quantitative data on the menopausal   with three parameters were given as:
            age of Nepalese women to analyze the distributional pattern   α   x −γ   α− 1
            stochastically so the ontological position of this research        
            was objectivism. We tried to establish the probabilistic   f  ( ) x =  β  β      , for x > γ    (3)
            relationship between the age of women at menopause as   2        x −γ    α   2
            the independent variable and the probability of menopause     1+     
            at  a  specific  age  as  the  dependent  variable.  Hence,  the         β     
            epistemological position of this research was positivism.
                                                                             x −γ   α
            3.1. Data                                                          β   
            To analyze the age at menopause, two secondary data sets   F 2 ( ) x =  α  , for x > γ         (4)
            were taken. The first one was from the cross-sectional survey       1+   x −γ      
            entitled “Demographic Survey on Fertility and Mobility”             β       
            conducted in two rural districts of Nepal taken from Aryal
            & Yadava (2005). The sample survey consisted of 811   Where  α,  β > 0 represent the shape and scale of the
            households comprised of a sample of 1019 married females   distribution. When the shape parameter  α is greater
            and 114 reached menopause. The second data set was taken   than one, the LLog distribution is a uni-model. The basic
            from Koirala & Manandhar (2018) where they collected data   properties of the LLog distribution were found in the
            about the menopausal age from 154 women from the 240   previous studies (Kleiber  & Kotz, 2003;  Lawless, 2003;
            respondents aged 45–60 who visited the district hospital.  Ashkar and Mahdi, 2006). The  k order moments were
                                                                                          th
                                                               derived by Tadikamalla (1980) for k < α and the moment
            3.2. Probability distribution models               had been derived and expressed as:
            To model the age at menopause of Nepalese women,                     k
            different probability distributions have been applied. The   EX k  k    πβ
                                                                   ( ) = γ+
            mathematical expressions of the models used to fit the          α sin kπ                       (5)
            distributional  pattern  of  age  at  menopause  of  Nepalese       α
            women were expressed in the following subsections.   In particular, the mean of the LLog distribution is
            3.2.1. Logistic probability distribution           γ +  πβ π   for  α > 1 and the variance is
            If  x represents the age at menopause of women, then   αsin α
            the probability density function (PDF) and cumulative               2
            distribution function (CDF) that follow a logistic distribution   2    
            were given as:                                       2πβ      −     πβ      for  α> 2 .
                            x−                                   2π       π   α
                            γ
                         −                                   α  sin     sin  
                        e   β                                     α        α
               fx () =                                  (1)
               1
                         −   x−   2                        3.2.3. Weibull distribution
                              γ
                     β  1+ e    β    
                                                               The PDF and CDF of the two-parameter Weibull
                                                             distribution were expressed in the following equations:
            Volume 1 Issue 2 (2023)                         3                        https://doi.org/10.36922/ghes.1239
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