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Gene & Protein in Disease Pre-metastatic niche oral cancer: Insights

Table 4. (Continued)
Term % P‑value Genes Fold Bonferroni Benjamini FDR
enrichment
hsa05212: Pancreatic 0.85106383 0.01240542 PIK3CG, BRAF, ARHGEF6, 1.86400293 0.89942723 0.06723523 14.3005254
cancer PIK3CD, TP53, SMAD4, NFKB1,
MAPK1, ACVR1B, KRAS, RAC2,
CASP9, IKBKG, PIK3CA, PIK3R5,
MAPK8, AKT3, AKT2
hsa04920: 0.80378251 0.0134903 CPT1C, TNF, RXRB, NFKBIE, 1.89182387 0.91784186 0.07086684 15.457126
Adipocytokine CHKB, NFKB1, PRKCQ,
signaling pathway TNFRSF1B, SLC2A4, IKBKG,
MAPK8, PRKAA1, JAK2, AKT3,
ACSL6, ACSL5, AKT2
hsa04720: Long-term 0.80378251 0.01552483 PRKCA, ADCY1, BRAF, CREBBP, 1.86400293 0.94380761 0.07896423 17.5875715
potentiation ITPR1, PRKCB, SPDYA, MAPK1,
RPS6KA3, EP300, KRAS,
CAMK4, GRIN2B, RPS6KA2,
PPP3CB, RAP1A, PLCB2
hsa05213: Endometrial 0.66193853 0.01702413 PIK3CG, MAPK1, TCF7, KRAS, 2.00738777 0.95754923 0.08402059 19.1258565
cancer CASP9, BRAF, PIK3CD, TP53,
LEF1, PIK3CA, PIK3R5, AXIN2,
AKT3, AKT2
hsa04012: ErbB 0.94562648 0.01939838 PRKCA, PIK3CG, BRAF, STAT5A, 1.71402569 0.97279559 0.09282107 21.5079322
signaling pathway MAP2K4, STAT5B, PIK3CD,
SRC, PRKCB, MAPK1, CBLB,
KRAS, CDKN1B, PLCG1, PLCG2,
PIK3CA, PIK3R5, MAPK8, AKT3,
AKT2
hsa04010: MAPK 2.26950355 0.02668452 FGFR1, FGF5, TNF, MAP4K2, 1.3404066 0.99310287 0.12275106 28.4213699
signaling pathway FASLG, MAP4K1, NFKB1,
NFKB2, MAP3K7, ACVR1B,
KRAS, MAP3K3, RAC2,
RASGRP3, RASGRP1, MAP3K8,
RASGRP2, PPP3CB, AKT3,
RASA2, AKT2, PTPN7, PRKCA,
BRAF, NF1, MAP2K4, CACNA1I,
TP53, ECSIT, MECOM,
CACNA2D3, STK4, PRKCB,
RPS6KA5, MAPK1, PLA2G4A,
RPS6KA3, DUSP2, RPS6KA2,
IKBKG, CACNA1H, RAP1A,
MAPK8, CACNA1F, MAP3K14,
PLA2G2D, CACNA1A, MAP3K12
hsa05222: Small cell 0.89834515 0.02694822 TRAF1, COL4A4, PIK3CG, FHIT, 1.68647884 0.99343832 0.12092479 28.6607497
lung cancer RXRB, PIK3CD, TP53, NFKB1,
BIRC3, CCNE2, CDKN1B, PIAS4,
CASP9, IKBKG, PIK3CA, PIK3R5,
TRAF5, AKT3, AKT2
hsa04960: 0.52009456 0.0400502 PRKCA, PIK3CG, MAPK1, 2.00039339 0.99945834 0.17140329 39.6685018
Aldosterone- KRAS, PIK3CD, NR3C2, PIK3CA,
regulated sodium PIK3R5, ATP1A2, SLC9A3R2,
reabsorption PRKCB
hsa00604: 0.28368794 0.04024494 ST3GAL1, ST6GALNAC4, 2.98240469 0.99947819 0.1683523 39.8196398
Glycosphingolipid ST3GAL5, B3GALT4, ST8SIA5,
biosynthesis ST8SIA1
(Cont’d...)

Volume 3 Issue 4 (2024) 15 doi: 10.36922/gpd.2971