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Global Translational Medicine AA amyloidosis in rheumatoid arthritis

Cl+/Cl- – – – – – – – – Cl+ – – Cl+ – – – – – – – – – Cl+ Cl+ – – – – – – (Cont'd...)

CoD – cAAa – – cAAa – – – rAAa-U cAAa cAAa rAAa-U cAAa – – cAAa rAAa-U – rAAa-U rAAa-U cAAa rAAa-U rAAa-U cAAa rAAa-U rAAa-U rAAa-U rAAa-U rAAa-U

Severity (amount) in % 0.72 2.46 3.33 3.54 5.72 8.40 8.60 9.26 10.83 11.27 11.70 13.11 14.19 14.40 14.49 14.56 14.93 17.48 18.97 19.75 24.60 26.27 28.53 30.16 30.50 31.42 32.11 34.10 34.16
Table 3. Prevalence and amount of amyloid A deposits in various organs of 34 rheumatoid arthritis patients with systemic amyloid A amyloidosis

Prevalence in % 25.00 37.50 28.57 37.50 50.00 75.00 66.67 100.00 50.00 87.50 62.50 71.43 75.00 71.43 62.50 50.00 75.00 50.00 85.71 75.00 85.71 85.71 75.00 87.50 75.00 100.00 100.00 85.71 85.71

“+” n 2 3 2 3 4 6 4 4 3 7 5 5 6 5 5 4 6 4 6 6 6 6 6 7 6 3 6 6 6

“0” n 6 5 5 5 4 2 2 0 3 1 3 2 2 2 3 4 2 4 1 2 1 1 2 1 2 0 0 1 1

Avg of sAAa/Pt 0.022 0.074 0.100 0.106 0.172 0.252 0.258 0.278 0.325 0.338 0.351 0.393 0.426 0.432 0.435 0.437 0.448 0.524 0.569 0.593 0.738 0.788 0.856 0.905 0.915 0.943 0.963 1.023 1.025

Sum 0.173 0.590 0.700 0.850 1.373 2.015 1.548 1.111 1.950 2.705 2.808 2.754 3.406 3.024 3.477 3.494 3.583 4.195 3.984 4.740 5.166 5.516 6.846 7.238 7.321 2.828 5.780 7.162 7.173

Count 8 8 7 8 8 8 6 4 6 8 8 7 8 7 8 8 8 8 7 8 7 7 8 8 8 3 6 7 7

Avg of sAAa/Pt 0.022 0.074 0.100 0.106 0.172 0.252 0.258 0.278 0.325 0.338 0.351 0.393 0.426 0.432 0.435 0.437 0.448 0.524 0.569 0.593 0.738 0.788 0.856 0.905 0.915 0.943 0.963 1.023 1.025

Brain 0 0 0 0 0 0 ND ND 0 0 0 0 0 0 0 0 0 0 0 0 0 ND 0 0 0 ND ND 0 0

Skin 0 0 0 0.4 0 0 ND ND 0 0.6 0 0 0 ND 0 0 0 0 ND 0 ND 0 1 0.5 0 ND 0.2 ND ND

Lung 0.083 0.000 0.000 0.000 0.000 0.167 0.000 0.167 0.000 0.167 0.167 0.417 0.167 0.000 0.750 0.000 0.250 0.000 0.750 0.333 0.250 0.333 0.417 0.333 0.833 0.417 0.917 1.167 0.917

Liver 0.000 0.000 0.000 0.000 0.000 0.111 0.111 0.111 ND 0.111 0.111 0.667 0.556 0.111 0.000 0.444 0.333 1.778 0.167 0.667 0.556 1.000 0.889 0.778 1.111 1.111 ND 1.222 0.889

GI tract 0.09 0.09 0.45 0.35 0.39 0.52 0.27 ND ND 0.61 1.08 0.52 0.15 1.18 0.41 0.85 0.85 0 0.7 0.64 0.76 0.45 1.64 1.16 1.06 ND 0.68 1.34 0.65

Pancreas 0.000 0.100 ND 0.100 0.400 0.200 0.500 ND 0.400 0.400 0.000 ND 1.000 0.550 0.650 0.800 0.300 0.100 0.700 1.200 1.100 0.600 0.000 1.400 1.300 ND 1.000 1.350 1.800

Heart 0.000 0.400 0.000 0.000 0.500 0.600 0.000 0.500 0.800 0.400 1.200 0.400 0.700 1.100 1.000 1.400 1.100 1.400 1.000 0.400 1.500 1.300 1.400 0.900 1.600 1.300 1.400 1.000 1.000

Kidney 0.000 0.000 0.250 0.000 0.083 0.417 0.667 0.333 0.750 0.417 0.250 0.750 0.833 0.083 0.667 0.000 0.750 0.917 0.667 1.500 1.000 1.833 1.500 2.167 1.417 ND 1.583 1.083 1.917

Pr. n 0] /y 155/87 243/87 76/79 240/88 287/91 226/85 183/92 266/78 306/90 430/80 395/76 80/80 322/81 162/78 52/92 45/74 342/86 90/85 203/88 39/76 245/88 232/74 265/80 367/75 73/87 V/T 137/76 43/85 174/88

f/m F F F F F F F F F F F F F F F F M F F F F M F F F F F M F

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Volume 4 Issue 1 (2025) 112 doi: 10.36922/gtm.5325