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Global Translational Medicine





                                        PERSPECTIVE ARTICLE
                                        Personalized and precision medicine as a

                                        health-care model of the next step generation
                                        through translational applications of individualized

                                        nutrition- and food design-driven resources



                                        Sergey Suchkov 1,2,3,4,5,6,7 * , Robert H. Lustig 8  , Marlene Escobedo-Monge 9,10,11 * ,
                                        Sofia Blokh 12  , Natalya Andronova 13  , Olga Goryacheva 14,15  ,
                                        Marina Borisovna Moyseyak 16  , Timur Vlasov 17  , Veronika Polyakova 18  ,
                                        Elena Antonova 19  , and Aleksandr Tuykavin 17

                                        1 Center for Biodesign, N.D. Zelinsky Institute for Organic Chemistry of the Russian Academy of
                                        Sciences, Moscow, Russia
                                        2 China Hong Kong Innovation International Business Association, Hong Kong SAR, China
                                        3 The New York Academy of Sciences, New York, United States of America
                                        4 The European Association for Predictive, Preventive and Personalized Medicine, Brussels, Belgium
                                        5 International Society of Personalized Medicine, Tokyo, Japan
                                        6 Personalized Medicine Coalition, Washington, United States of America
                                        7 American Chemical Society, Washington, United States of America
            *Corresponding authors:     8 Division of Endocrinology, Department of Pediatrics, University of California, San Francisco,
            Sergey Suchkov              California, United States of America
            (ssuchkov57@gmail.com)      9 Department of Pediatrics, Faculty of Medicine, University of Valladolid, Valladolid, Spain
            Marlene Escobedo-Monge
            (amescobedo@msn.com)        10 International Cooperation for Health and Social Development Group, University of Las Palmas de
                                        Gran Canaria, Canary Islands, Spain
            Citation: Suchkov S, Lustig RH,   11 Area of Endocrinology, Diabetes, and Nutrition, Institute for Health Research (IBioVALL), Valladolid,
            Escobedo-Monge M, et al.
            Personalized and precision   Spain
            medicine as a health-care model   12 Department of General Hospital, Filatov Children’s City Clinical Hospital, Moscow, Russia
            of the next step generation through   13 Department of Moscow City, Grand Clinic Moscow, Moscow, Russia
            translational applications of
            individualized nutrition- and food   14 Department of Propaedeutics of Childhood Diseases, Pediatric Faculty, Institute of Maternal and
            design-driven resources. Global   Childhood, Pirogov Russian National Research Medical University, Moscow, Russia
            Transl Med. 2025;4(3):60-82.   15 Department of Gastroenterology, Morozovskaya Children’s City Clinical Hospital, Moscow, Russia
            doi: 10.36922/GTM025080017
                                        16 Institute of Food Systems and Health-saving Technologies, Faculty of Technology of Fermentation
            Received: February 20, 2025  and Winemaking, Moscow, Russia
            Revised: July 14, 2025      17 Department of Pathophysiology, Faculty of Medicine, Pavlov First Saint Petersburg State Medical
                                        University, Saint Petersburg, Russia
            Accepted: August 11, 2025
                                        18 Department of Personalized Medicine, Precision Nutrition and Biodesign, Institute of Biotechnology
            Published online: September 3,   and Global Health, BIOTECH University, Moscow, Russia
            2025                        19 Department of Statistics, Filatov Children’s City Clinical Hospital, Moscow, Russia
            Copyright: © 2025 Author(s).
            This is an Open Access article
            distributed under the terms of the   Abstract
            Creative Commons Attribution
            License, permitting distribution,
            and reproduction in any medium,   In the modern era, health is a key element in shaping the trajectory of human
            provided the original work is   civilization.  The personalized and precision medicine model is a preventive
            properly cited.             strategy capable of operating across a wide range of technological applications,
            Publisher’s Note: AccScience   from biomarker-driven genomic profiling to determine the characteristics of an
            Publishing remains neutral with   individual’s  genomic  landscape,  to  combinatorial  assessments  of  the  individual’s
            regard to jurisdictional claims in
            published maps and institutional   interaction with the microenvironment for constructing the individual phenotype.
            affiliations.               Omics technologies demonstrate their  multidisciplinary potential  in pre-clinical

            Volume 4 Issue 3 (2025)                         60                          doi: 10.36922/GTM025080017
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