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Global Translational Medicine Precision medicine via personalized nutrition

screening, predictive and prognostic diagnosis, multidimensional monitoring,
and targeted therapy, through the prism of preventive and curative rehabilitation
strategies concerning a particular individual, as well as the principles and resources
of genomic biostatistics and molecular epidemiology at the population and national
levels. Therefore, this article aims to highlight the omics approach to nutritional
assessment and dietary recommendations from the individual to the population
level.

Keywords: Omics technology; Genetics; Proteomic; Metabolomic; Biomarkers;
Interactomics

1. Introduction metabolomics, and microbiomics, has significantly
enhanced our ability to interpret genomic data
The progress of health-saving technologies has substantially and improve health outcomes. By integrating these
transformed modern health care, presenting personalized interconnected datasets, integrative multiomics offers a
approaches that are both pioneering and effective. Among more comprehensive understanding of human health and
these, personalized nutrition (PN) and precision foodomics
(PF) have emerged as significant fields, taking advantage disease. Health-saving technologies, embedded within the
of the power of omics technologies to provide tailored infrastructure of the model of personalized and precision
medicine (PPM), represent a unique preventive strategy
nutritional advice and interventions. This personalized (Figures 3 and 4).
approach is critical for addressing the unique health needs
of individuals, enhancing overall well-being, and preventing Multiomics technologies operate with large amounts
nutrition-related diseases. In this context, the main objective of data to identify the relationships between biological
of PN and PF is to promote and improve health by utilizing processes at various levels, the dynamics of borderline
omics, phenotypic, medical, nutritional, and other relevant states with induction of pathological processes, and the
personal data to provide more precise dietary guidance development of optimal protocols for targeted therapy.
and customized nutritional products and services. These With the introduction and study of systems omics
approaches can be applied to patients, individuals at risk, technologies, the mechanisms of induction, development,
and healthy individuals, regardless of whether they have and progression of chronic health conditions, including
a genetic predisposition to specific disorders, including nutritional and hereditary conditions, have moved from
metabolic and nutritional conditions (Figures 1 and 2). hypothetical approaches to diagnosis, treatment, and
1-8
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Health-saving technologies aim to prevent and prevention to integrated strategies (Figures 5 and 6).
delay illnesses, improve well-being, and reduce health- Omics technologies, including genomics, proteomics,
care needs, with nutrition being a key determinant of metabolomics, and microbiomics, are at the forefront
individual health outcomes. Diets can increase disease of PPM. These technologies offer an in-depth analysis
risk or promote better health depending on their genetic of biological molecules, revealing intricate interactions
impact. Nutrigenomics explores the connection between among genes, proteins, and metabolites. By integrating
food and genetics and facilitates innovations in health multiomics data, researchers and health-care providers
care. Developments in wearable devices and artificial can enhance their understanding of an individual’s overall
intelligence (AI)-assisted diagnostics empower individuals health condition, facilitating precise and personalized
and enable individualized, patient-centered care. These interventions. The omics technologies applied in PN are
technologies help improve health-care access and ensure particularly transformative. Nutrigenomics, a subfield of
quality medical expertise is available to all. By adopting omics, studies how food affects gene expression and how
these innovations, we can transform health care and build genetic variations alter the body’s response to nutrients.
a healthier, more resilient world for everyone. This knowledge allows for the development of dietary

2. Omics technologies: The new generation proposals tailored to the genetic predispositions of each
individual, improving health outcomes and preventing
of health-saving technologies chronic diseases. Several fundamental areas of omics
The development of multiomics technologies, which technology and their potential applications are discussed
include transcriptomics, proteomics, epigenomics, in the following sections.

Volume 4 Issue 3 (2025) 61 doi: 10.36922/GTM025080017