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Global Translational Medicine                                     Precision medicine via personalized nutrition


































            Figure 13. Overview of the elements and activities that constitute a fully integrated personalized nutrition (PN) service. PN is rapidly gaining traction as
            an innovative approach to guiding individuals toward informed dietary choices. It is built on two fundamental pillars: (i) The scientific, analytical, and
            technological components that ensure the accuracy and effectiveness of nutritional recommendations, and (ii) the equally vital behavioral dimension
            that ensures these recommendations are practical and actionable. While the growing interest in PN aligns with strong societal trends, delivering such a
            service will require innovative strategies beyond those currently employed by traditional nutrition and health-care sector stakeholders. It is likely that a
            new ecosystem of interconnected companies will emerge to meet this evolving demand. By shaping food choices, PN has the potential to exert a profound
            influence on the food supply chain and on the way information about ingredients and products is communicated to consumers. 87

               objectives. These plans may include detailed recipes   As shown in Figure 14, the potential market for PN is huge.
               and portion sizes tailored to the individual.   Most  commercial  PN-driven  interventions  are  delivered
            (iii). Behavioral tracking: PN tools assist users in   directly to consumers by online platforms. The public
               monitoring their progress toward defined health goals,   shows a strong interest in receiving PN guidance; however,
               providing feedback and recommendations to enhance   concerns regarding the reliability of certain primary care
               motivation and adherence.                       service providers, the  credibility of information  sources,
            (iv). Remote coaching and support: Digitalization enables   and the security of personal data remain. Other influencing
               individuals to interact remotely with nutritionists,   factors include individuals’ preferences for primary care
               dietitians, and other health professionals. Through   services and their diverse socioeconomic backgrounds.
               video consultations and messaging, individuals can   In this regard, direct-to-consumer DNA testing serves
               obtain PN advice and support without the need for   as an example of primary care services available to the
               in-person visits, making  the  overall process more   public. 89-91  In this context, guiding principles should be
               convenient.                                     applied when designing and implementing PN research,
            (v).  Integration with e-commerce: Digital platforms can   considering its multidisciplinary nature.  Designers,
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               connect health-conscious users with PN products and   researchers, and dietitians should collaborate to conduct
               supplements available on e-commerce sites, making   a thorough review of PN research, utilizing a standardized
               it more convenient to follow their customized dietary   definition to guide the development of future NP-driven
               plans.                                          practices. This effort should also address challenges arising
              Digitalization plays a  significant  role in  addressing   from rapid technological advancement and the lack of
            challenges by leveraging technology to analyze health data,   consensus on integrating these tools into clinical settings.
            disseminating knowledge and awareness related to PN and PF,   Establishing  stakeholder  consensus on  standardized
            and facilitating remote consultations with nutrition experts.   methods for implementing multiomics technologies and
            As digitalization stakeholders continue to expand into this   IT-assisted support could accelerate their adoption in
            domain, the PN market is expected to experience further   clinical practice, enhancing NP-based recommendations
            disruptions and cross-industry collaborations (Figure 14).  for disease prevention and treatment. When vital research


            Volume 4 Issue 3 (2025)                         73                          doi: 10.36922/GTM025080017
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