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International Journal of Bioprinting Advancements in 3D printing

achieved remarkable breakthroughs in this domain. At by computer-assisted imaging, 3D bioprinting technology
Tsinghua University, Sun et al. group produced animal empowers the meticulous creation of tailored scaffolds
hearts using cardiomyocytes and biomaterials. The printed that faithfully replicate the intricate 3D framework of
cells demonstrated rhythmic beating, suggesting potential impaired tissues and organs. These scaffolds, coupled
functionality of the printed organs. Furthermore, they with seed cells and scaffold materials, acquire biological
3D-printed stem cells extracted from amniotic fluid functionality. As a result, 3D bioprinting has drawn
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and incorporated bone differentiation factors to achieve substantial interest within the sphere. In 1990, Chuck
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activation. This innovation can address periodontal tissue Hull first introduced the concept of 3D printing. Since
defects. Following printing and cultivation, the product the 1990s, 3D printing technology has rapidly advanced.
exhibited an organized structure with physiological The initial 3D bioprinter was developed by Wilson and
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functions. This team also pioneered essential bioprinting Boland. In contrast to traditional flat printing, 3D
technology, resulting in novel biological patents for a precise printing entails the creation of 3D objects. It operates on
stem cell culture system featuring biomimetic capabilities. the principles of additive manufacturing, where layers are
China’s rapid strides in the advancements of 3D printing progressively deposited to form a complex 3D structure.
technology for artificial organ have enabled its permeation This diverges from conventional manufacturing methods
into diverse applications, including medical implants. like subtractive manufacturing and molding. As one of the
These advancements hold immense potential for the future disruptive technologies shaping the forthcoming economy
of regenerative medicine and healthcare (Figure 1). and human existence, 3D printing seamlessly amalgamates
diverse disciplines, including materials science, machinery
Leveraging strides in both life science and manufacturing, information technology, electronics,
manufacturing, 3D printing has found wide-ranging and engineering design. It surmounts the limitations
applications within biomedical domains encompassing encountered by conventional manufacturing in dealing with
surgery, dentistry, tissue engineering, regenerative intricate structures. 3D printing permits the production of
medicine, and pharmaceutical formulation. Empowered tailored and personalized items, significantly improving
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Figure 1. A timeline depicting the advancements of 3D bioprinting.

Volume 10 Issue 2 (2024) 46 doi: 10.36922/ijb.1752