Page 446 - IJB-10-3

International Journal of Bioprinting Different modeling of porous scaffolds

mechanical and permeability properties of the porous Author contributions
scaffolds. The summarized results are as follows:
Conceptualization: Binghao Wang, Chengliang Yang
(i) The mechanical properties of the scaffolds prepared Formal analysis: Zheng Shi
through thickening and filling strategies were Investigation: Chuanchuan Zheng
comparable to the mechanical properties of human Methodology: Wen Peng
bones. The elastic modulus (ranging from 3.03 to Writing – original draft: Binghao Wang, Miao Luo
4.57 GPa) for different scaffolds within the range of Writing – review & editing: Yuting Lv, Liqiang Wang
human bones and their ultimate strength (ranging
from 135.78 to 250.90 MPa) met the biomechanical Ethics approval and consent to
requirements of orthopedic applications. participate
(ii) Compared to the filling structure, the thickening Not applicable.
strategy can improve the compressive strength and
toughness of G, D, and IW-P scaffolds and reduce Consent for publication
stress fluctuations during the collapse process.
Not applicable.
(iii) The permeability of the scaffolds ranges from 0.88
to 1.91 × 10 m , which is close to the permeability Availability of data
2
-9
of human bone. Filling structures exhibit higher Data are available from the corresponding author upon
permeability than thickening structures, mainly due reasonable request.
to the significantly smaller specific surface area of
the filling structure and larger pore size. References
(iv) Thickening strategy fundamentally adjusts the material
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design can focus on the requirements for load, cell
adhesion, modulus, and other factors, leveraging 2. Fang Y, Wang Q, Yang Z, et al. An efficient approach to
the advantages of thickened structures in terms of endow TiNbTaZr implant with osteogenic differentiation
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Acknowledgments
3. Zhang Y, Attarilar S, Wang L, Lu W, Yang J, Fu Y. A
The authors extend their gratitude to Guangxi Key review on design and mechanical properties of additively
Laboratory of Basic and Translational Research of Bone manufactured NiTi implants for orthopedic applications. Int
and Joint Degenerative Diseases and Guangxi Biomedical J Bioprint. 2021;7(2):340.
Materials Engineering Research Center for Bone and doi: 10.18063/ijb.v7i2.340
Joint Degenerative Diseases for providing experimental 4. Qu H. Additive manufacturing for bone tissue engineering
equipment and technology. In addition, the authors thank scaffolds. Mater Today Commun. 2020;24:101024.
Xiaoli Ma at the Instrumental Analysis in Shanghai Jiao doi: 10.1016/j.mtcomm.2020.101024
Tong University for her guidance on experimental testing 5. Yuan L, Ding S, Wen C. Additive manufacturing technology
and analysis. We thank Guangxi Key Laboratory of Basic for porous metal implant applications and triple minimal
and Translational Research on Bone and Joint Degenerative surface structures: a review. Bioact Mater. 2019;4:56-70.
Diseases (21-220-06) for the financial support. doi: 10.1016/j.bioactmat.2018.12.003
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Funding manufacturing of porous metals for bone scaffolds and
The authors acknowledge the financial supports from orthopaedic implants: a review. Biomaterials. 2016;83:
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National Natural Science Foundation of China (Grant Nos. doi: 10.1016/j.biomaterials.2016.01.012
52274387 and 52311530772).
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Conflict of interest properties of porous titanium compacts prepared by powder
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The authors declare no conflicts of interest. doi: 10.1016/j.scriptamat.2003.08.018

Volume 10 Issue 3 (2024) 438 doi: 10.36922/ijb.2565