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Hu, et al.

Figure 3. Case 1. CT imaging at the post-operative nine-month follow-up visit. Coronal and sagittal CT images show evident bone ingrowth
and good biological fusion between the porous interface of the 3D-printed prosthesis and the autogenous vertebral endplate (red arrow).

A B

C D

Figure 4. Case 2. (A) Pre-operative MRI and PET-CT showing recurrent tumors on T4, T5, and T6; (B) 3D imaging visually showing T4~6,
planned for resection and replacement with patient-specific 3D-printed artificial vertebral body; (C) final titanium alloy implant, including
solid and porous parts; (D) post-operative X-ray showing excellent implant fit, stability, and alignment.

performed. Postoperative X-ray and 3D-imaging (5) Case 5
demonstrated an excellent position and stability of the
titanium vertebral body implant (Figure 6C). During A 31-year-old female presented with neck and shoulder
3-month-follow-up after the surgery, the patient moved pain, and paralysis of the right upper limb. She was found
freely and had no pain and no local recurrence. She was to have a C6 tumor and underwent anterior cervical
recommended to receive adjuvant chemotherapy. decompression and internal fixation in another hospital

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