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International Journal of Bioprinting


                                        RESEARCH ARTICLE
                                        RESEARCH ARTICLE
                                        The design and processing of a 3D-printed
                                        high-performance biological fixation plate



                                        Guoqing Zhang *, Junxin Li , Xiaoyu Zhou , Yongsheng Zhou ,  Bai Yuchao
                                                                1
                                                     1
                                                                            1
                                                                                                        2, 3
                                                                                            1
                                        1 School of Mechanical and Electrical Engineering, Zhoukou Normal University, Zhoukou 466000,

                                        Henan, P.R. China
                                        2 School of Mechanical and  Automotive Engineering,  South China University of  Technology,
                                        Guangzhou 510640, Guangdong, P.R. China
                                        3
                                        Department of Mechanical Engineering, College of Design and Engineering, National University of
                                        Singapore, 9 Engineering Drive 1, Singapore 117575, Singapore
                                        Abstract
                                        In order to generate a high-performance personalized biological fixation plate with
                                        matching mechanical properties and biocompatibility, reverse reconstruction and
                                        fracture reduction of a femur were performed by combining reverse and forward
                                        approaches, and the surface was extracted according to the installation position of
                                        the plate to complete plate modeling by shifting, thickening, and performing other
                                        operations. Subsequently, topology optimization and three-dimensional (3D) print-
                                        ing were performed, and the properties of the manufactured plate were probed. The
                                        results showed that the maximum displacement of the plate was 4.13 mm near the
                                        femoral head, the maximum stress was 5.15e  MPa on both sides of the plate across
                                                                             2
                                        its entire length, and the stress concentration decreased following topology opti-
                                        mization. The plate with optimized topology and filled with porous structure has a
                                        good filling effect. The final mass of the H-shaped plate was 12.05 g, while that of
            *Corresponding author:      the B-shaped plate was 11.05 g, which dropped by 20.93% and 27.49%, respective-
            Guoqing Zhang               ly, compared with the original plate. The surface of the 3D-printed plate was bright
            (zhangguoqing1202@sohu.com)
                                        and new, with a clear pore structure and good lap joint. The B-shaped and H-shaped
            Citation: Zhang G, Li J, Zhou X,   plates were closely dovetailed with the host bone, which met the assembly require-
            et al., 2023, The design and
            processing of a 3D-printed high-  ments. This lays a foundation for the direct application of a high-performance per-
            performance biological fixation plate.   sonalized biological fixation plate.
            Int J Bioprint, 9(2): 658.
            https://doi.org/10.18063/ijb.v9i2.658
                                        Keywords: Selective laser melting; Bone plate; Topological optimization; Simulation
            Received: July 15, 2022
            Accepted: August 26, 2022   analysis; Forming quality
            Published Online: December 30,
            2022
            Copyright: © 2022 Author(s).
            This is an Open Access article   1. Introduction
            distributed under the terms of the
            Creative Commons Attribution   Bone diseases, bone trauma, congenital malformations of the bone, and other bone-
            License, permitting distribution
            and reproduction in any medium,   related diseases are treated with internal fixation with plates. The properties of these
                                                                            [1]
            provided the original work is   plates are critical for successful osteosynthesis . The two factors that affect the properties
            properly cited.             of plates are as follows [2,3] : (1) ideal plate material should have high strength, low stiffness,
            Publisher’s Note: Whioce    similar elastic modulus to human bone (to avoid “stress shielding”), no toxicity or
            Publishing remains neutral with   rejection, and good biocompatibility; (2) in terms of structural design, there should
            regard to jurisdictional claims in   be fewer screw holes for fixation. Several researchers have found that using too many
            published maps and institutional
            affiliations.               screws might cause stress concentration and damage the plate, whereas using too few

            Volume 9 Issue 2 (2023)                        118                      https://doi.org/10.18063/ijb.v9i2.658
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