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Journal of Clinical and
            Translational Research                                                  ROCK inhibition in chronic rejection




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            Figure 3. Comparison of downregulated genes between Rezurock/fingolimod combination treatment and Rezurock-only treatment in mouse macrophages.
            (A and B) Venn diagrams showing the overlap of downregulated genes in Rezurock/fingolimod combination treatment and Rezurock-only treatment.
            (C) GO analysis of downregulated genes specific to the Rezurock/fingolimod combination treatment. (D) GO analysis of downregulated genes specific to
            the Rezurock-only treatment. (E) GO analysis of downregulated genes common to both Rezurock/fingolimod combination and Rezurock-only treatments.
            Abbreviations: GO: Gene ontology; ECM: Extracellular matrix; NTR: Non-catalytic tyrosine-phosphorylated receptor; TP53: Tumor protein 53.


            Volume 11 Issue 5 (2025)                        85                         doi: 10.36922/JCTR025270036
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