Page 92 - JCTR-11-5

Journal of Clinical and
Translational Research ROCK inhibition in chronic rejection

A B

C

D

E

Figure 4. Comparison of upregulated genes between Rezurock/fingolimod combination treatment and Rezurock-only treatment in mouse macrophages.
(A and B) Venn diagrams comparing upregulated genes between the Rezurock/fingolimod combination treatment and Rezurock-only treatment. (C) GO
analysis of upregulated genes specific to the Rezurock/fingolimod combination treatment. (D) GO analysis of upregulated genes common to both the
Rezurock/fingolimod combination and Rezurock-only treatments. (E) GO analysis of upregulated genes specific to the Rezurock-only treatment.
Abbreviations: GO: Gene ontology; CoA: Coenzyme A; ER: Endoplasmic reticulum; MAPK: Mitogen-activated protein kinase; Rho: Ras homolog family
member.

Volume 11 Issue 5 (2025) 86 doi: 10.36922/JCTR025270036