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Microbes & Immunity Comprehensive genomic surveillance analysis of SARS-CoV-2

Figure 5. Fold increase in reproductive number against date of lineage emergence of SARS-CoV-2 over time. Fold increase in reproductive number against
date of lineage emergence of SARS-CoV-2 over time (as of August 15, 2022), colored by variants of concern/interest. The top 10 lineages with the number
of cases are labeled. Data were obtained from publicly released data provided by the Broad Institute of and Harvard (http://www.broadinstitute.org/) in the
pyro-cov data repository (https://github.com/broadinstitute/pyro-cov). 7

health efforts. This study emphasizes the importance of timely Author Contributions
outbreak detection amidst increasing human activities. It
calls for an allocation of enhanced resources and focused Conceptualization: Xingguang Li
efforts on controlling epidemics, especially in LMICs, with Investigation: Xingguang Li
the aim of refining and bolstering global health responses. Writing – original draft: Xingguang Li
Writing – reviewing & editing: Haizhou Liu, Yigang Tong
Acknowledgments
Ethics approval and consent to participate
The authors are grateful to Dr. Wytamma Wirth from
the Peter Doherty Institute for Infection and Immunity, Not applicable.
University of Melbourne, Melbourne, Victory, Australia,
for technical support. In addition, appreciation is extended Consent for publication
to Prof. Rajendram Rajnarayanan from the New York Not applicable.
Institute of Technology, College of Osteopathic Medicine,
Arkansas State University, and Prof. Aaron T. Irving Availability of data
from the Department of Clinical Laboratory, the Second Not applicable.
Affiliated Hospital, Zhejiang University, for their insightful
discussions. The authors are also grateful to the Authors References
and Originating and Submitting Laboratories for sharing
their sequences and meta-data through the GISAID 1. Zhu N, Zhang D, Wang W, et al. A novel coronavirus from
5
platform, upon which this research is based. patients with pneumonia in China, 2019. N Engl J Med.
2020;382:727-733.
Funding doi: 10.1056/NEJMoa2001017
None. 2. Brito AF, Semenova E, Dudas G, et al. Global disparities
in SARS-CoV-2 genomic surveillance. Nat Commun.
Conflict of interest 2022;13:7003.
The authors declare no conflict of interest. doi: 10.1038/s41467-022-33713-y

Volume 1 Issue 1 (2024) 110 doi: 10.36922/mi.2294