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Materials Science in Additive Manufacturing Water repellence via pinecone structures

of microfluidic chips with various customized micro/nano 2. Elvira K, Solvas XC, Wootton RC, et al., 2013, The past,
hierarchical features and tuned functions. There is a broad present and potential for microfluidic reactor technology in
potential application prospect for this technology. However, chemical synthesis. Nat Chem, 5: 905–915.
insufficient processing efficiency remains a significant https://doi.org/10.1038/nchem.1753
challenge. Incorporating TPP and other approaches will 3. Vitorino R, Guedes S, da Costa JP, et al., 2021, Microfluidics
offer a solution and allows cross-scale processing. for peptidomics, proteomics, and cell analysis. Nanomaterials

Acknowledgments (Basel), 11: 1118.
https://doi.org/10.3390/nano11051118
The authors express their gratitude to Dr. Liu Feng from
Analytical Testing Center, Shandong University of Technology, 4. Liu Y, Chen X, Zhang Y, et al., 2019, Advancing single-
cell proteomics and metabolomics with microfluidic
for her assistance in the characterization of the samples.
technologies. Analyst, 144: 846–858.
Funding https://doi.org/10.1039/c8an01503a
This work was financially supported by the National Key 5. Maurya R, Gohil N, Bhattacharjee G, et al., 2022,
R&D Program of China (grant number: 2022YFE0199100), Microfluidics for single cell analysis. Prog Mol Biol Transl
and Shandong Natural Science Foundation (grant numbers: Sci, 186: 203–215.
ZR2020QE030 and ZR2022ZD07). https://doi.org/10.1016/bs.pmbts.2021.07.013

Conflict of interest 6. Luo X, Chen JY, Ataei M, et al., 2022, Microfluidic
compartmentalization platforms for single cell analysis.
No potential conflicts of interest were reported by the authors. Biosensors (Basel), 12: 58.
Author contributions https://doi.org/10.3390/bios12020058
7. Filippi M, Buchner T, Yasa O, et al., 2022, Microfluidic tissue
Conceptualization: Wenhui Yu, Weilong Cao, Zhen Xiao engineering and bio-actuation. Adv Mater, 34: e2108427.
Formal analysis: Wenhui Yu, Weilong Cao, Zhen Xiao,
Yongling Wu https://doi.org/10.1002/adma.202108427
Funding acquisition: Wenhui Yu, Hongyu Zheng 8. Takehara H, Sakaguchi K, Sekine H, et al., 2019, Microfluidic
Investigation: Wenhui Yu, Weilong Cao, Wuhong Xin vascular-bed devices for vascularized 3D tissue engineering:
Methodology: Wenhui Yu, Weilong Cao, Zhen Xiao Tissue engineering on a chip. Biomed Microdevices, 22: 9.
Project administration: Wenhui Yu, Hongyu Zheng https://doi.org/10.1007/s10544-019-0461-2
Supervision: Wenhui Yu, Hongyu Zheng 9. Zhang Z, Guo Q, Wang Y, et al., 2023, High-throughput
Writing – original draft: Weilong Cao screening of microbial strains in large-scale microfluidic
Writing – review & editing: Wenhui Yu, Zhen Xiao, droplets. Front Bioeng Biotechnol, 11: 1105277.
Yongling Wu, Hongyu Zheng
https://doi.org/10.3389/fbioe.2023.1105277
Ethics approval and consent to participate 10. Carvalho RM, Ferreira VS, Lucca BG, et al., 2021, A novel
all-3D-printed thread-based microfluidic device with
Not applicable.
an embedded electrochemical detector: First application
Consent for publication in environmental analysis of nitrite. Anal Methods,
13: 1349–1357.
Not applicable. https://doi.org/10.1039/d1ay00070e
Availability of data 11. Yamada K, Shibata H, Suzuki K, et al., 2017, Toward
practical application of paper-based microfluidics for
Data related to this work can be acquired by contacting the medical diagnostics: State-of-the-art and challenges. Lab
corresponding author with a reasonable justification. Chip, 17: 1206–1249.

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Volume 2 Issue 2 (2023) 8 https://doi.org/10.36922/msam.0879