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Materials Science in Additive Manufacturing Preparation and modification of porous Ti

and then added mesoporous silica nanoparticles (MSNs) and For example, the surface morphology of porous titanium
mechanical growth factor (MGF) into the carbon nanotubes, cannot adapt with time to the continuous changes, posing
as shown in Figure 14. The results of biological experiments difficulty to the chemical composition released in response
show that the porous titanium coating has a nanostructured to a change in tissue growth and the human environment.
topological structure and can improve myoblasts’ adhesion, Using ultrasonic, electromagnetic, photothermal, and other
proliferation, and myogenic differentiation on the material’s external stimulation combined with special coatings, the
surface through covalent bond prolongation. function of the modified layer can be stimulated to achieve
The dynamic changes in the fluid environment and dynamic regulation and satisfy the conditions required
tissues present hurdles for the continual usage of implants. for human tissue recovery. As shown in Figure 15, Wu
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Figure 14. Multi-method composite construction coating. The porous prosthesis was coated with CNT and deposited to Ti-CNTS-MSNS@MGF.
Copyright © 2022 ACS. Reprinted with permission from ACS.
Abbreviations: CNTs: Carbon nanotubes; CTAB: Cetyltrimethylammonium bromide; EDC/NHS: N-hydroxysuccinimide and 1-ethyl-3-(3-
dimethylaminopropyl) carbodiimide hydrochloride; EPD: Electrophoretic deposition; MGF: Mechanical growth factor; MSNs: Mesoporous silica
nanoparticles; TEOS: Tetraethoxysilane; TMJ: Tendon muscle junction.

A

B C

Figure 15. Porous Ti6Al4V scaffold coated with barium piezoelectric titanate and implantation scaffold and mechanism of bone formation. Copyright
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© 2023 Elsevier. Reprinted with permission from Elsevier.

Volume 3 Issue 1 (2024) 18 https://doi.org/10.36922/msam.2753