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Materials Science in Additive Manufacturing                         Preparation and modification of porous Ti



            et al.  used a hydrothermal synthesis method to form   biocompatibility and ensure the primary conditions
                126
            BaTiO  coating uniformly on the surface of a 3D-printed   for their functioning, while the above properties can
                 3
            porous Ti6Al4V scaffold. The ultrasonic excitation    be influenced by the material composition, structural
            of coating vibration to generate electrical stimulation   design, and surface properties.
            promoted the pro-regenerative M2 polarization, inhibited   (ii)  The porous  structure  can reduce  elastic  modulus
            the M1 polarization of macrophages, and promoted the   and improve compatibility, in terms of mechanical
            bone regeneration process of the sheep cervical vertebra   properties, with the human body. The properties of
            resection model.                                      porous titanium are affected by the preparation process
                                                                  and structure. According to the sintering principle, the
              The principles, advantages, and disadvantages of    preparation process of porous titanium mainly includes
            different surface modification methods are summarized in   the sintering method, fiber preparation, additive
            Table 3.                                              manufacturing,  and so  on. With  the development

            5. Summary and outlook                                of  additive  manufacturing,  the  machining  accuracy
                                                                  and structural complexity of porous titanium will be
            Medical porous titanium alloy has broad development   continuously improved, alongside the steady develop
            prospects in biological tissue engineering. Through the   of a design scheme based on design elements such as
            review and summary of its performance requirements,   aperture, porosity, and structural units. In the future,
            processing  methods,  modification  methods,  and  effects,   additive manufacturing of porous titanium alloys
            the following conclusions are drawn:                  will take into consideration the development of new
            (i)  Medical porous titanium alloy in the human body   materials and the structural topology optimization
               mainly  plays  a fixed, supporting,  loading, and   for realizing the processing of structure-function
               other roles. Good mechanical properties (strength,   integrated  devices,  with  the  aim  of  enhancing  their
               modulus, corrosion/wear resistance) guarantee      performance in mimicking human tissue.


            Table 3. Comparison of different surface modification processes for porous titanium alloys
            Modified technology   Preparation principle  Working principle  Advantages   Disadvantages  References
            Physical modification  Alteration of the surface structure   Forms a certain rough   Low cost and easy to   Poorly effective  95
                               and roughness of the material by   structure on the surface of   operate
                                  means of etching, etc.  the material to promote cell
                                                             growth
            Chemical modification
             Chemical molecular   The coating is directly formed by   Influence cellular behavior   Low cost and   Low bonding   101
             dipping           a chemical reaction between the   by attaching chemicals to   effective  strength to the
                              modified solution and the surface of   surfaces            material surface,
                                     the material                                        prone to debris
                                                                                        and inflammation
             Vapor deposition   Attachment of the metal to   Acts on cells/bacteria via   Good coating   Limited metal   127
                                the surface of the material by   metallic components such as  bonding properties,  loading and thin
                               vaporization of the evaporated   Ag/Cu/Zn in the film  suitable for   modification layer
                              metal to produce a modified film by           metal element
                                      reaction                              modification
             Electrochemical   Electrochemical reaction causes the   The electrolyte component   Strong binding and   High cost   109
             modification     analytes in the electrolyte to adhere   and porous structure of the   good effect  and complex   107
                               to the surface of the material to   coating also promote cell   preparation   115
                                    form a coating           growth                         process
            Loaded drug or active   Bioactive substances such as drugs   Promote tissue recovery by   High safety and   High requirements   117
            substance          and cellular platelets are loaded   releasing drugs and building a   quick recovery  for surface coating   119
                               onto the surface of the material   bioactive environment   preparation
                                using a carrier such as a gel
            Compound method      Combining morphological   The synergistic action of   Better results with   High preparation   126
                               modification with compositional   different components, or   simultaneous   requirements and
                                effects, or building coatings   the joint action of surface   antimicrobial and   complex processes
                               from combinations of different   morphology and components  osteogenic effects
                                     components


            Volume 3 Issue 1 (2024)                         19                      https://doi.org/10.36922/msam.2753
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