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Figure 1. Flowchart illustrating the screening process for publications included in this bibliometric analysis. Dark blue blocks indicate sections retained
after each screening step, while light blue blocks indicate publications that were excluded.
Abbreviations: SCI: Science citation index; WoSCC: Web of science core collection.

Prism 8 (GraphPad Software, United States of America from 2010 to 2024. After excluding specific types of
[USA], www.graphpad.com), while R software (R Core documents – 18 meeting abstracts, four editorial materials,
Team, Austria, https://www.R-project.org/) and Python and one early access article – 288 publications were
libraries (including SciPy, Matplotlib, and NumPy) were selected for analysis. All included publications were in
used to generate visualizations, such as world maps. English (Figure 1). Figure 2A shows the annual number
Bibliometric analysis was conducted using CiteSpace of publications (blue bars) alongside the RRI (pink line)
(Chaomei Chen, Drexel University, USA, http://cluster. from 2010 to 2024. The number of publications steadily
cis.drexel.edu/~cchen/citespace/). WoS and GraphPad increased over time, with a noticeable rise after 2016,
Prism 8 were also used to analyze total publications from indicating growing research interest in the field of bone/
leading countries. The H-index, a metric that evaluates cartilage organoids (Figure 2A). The USA led the field with
a scholar’s impact based on the number of papers 103 publications, followed by China with 80, and Japan
published and cited at least H times, was calculated using with 25, while other countries, including Germany, the
GraphPad Prism 8. Author, institution, journal impact, Netherlands, and the United Kingdom, also contributed
24
and research orientation analyses were conducted using to the growing body of literature. (Figure 2B) The annual
relevant software. VOSviewer was utilized to create a publication trends from the top 10 most productive
literature network and analyze co-citation, co-occurrence, countries (Figure 2C) showed that the USA maintained a
and bibliographic coupling relationships. In addition, R dominant position in the field, with a noticeable increase in
was used to visualize publication trends and their global research output in recent years. China also demonstrated
interconnections. CiteSpace (version 6.1.R2) was employed rapid growth, narrowing the gap with the USA.
to identify citation bursts in significant journals, track 3.2. Bibliometric analysis of different countries and
strong citation bursts for keywords and references, and institutions
perform cluster analysis of keyword co-citation.
The citation and impact analysis of bone/cartilage
3. Results organoids research revealed a balance between research
quantity and quality across countries (Figure 3). The USA
3.1. Overall performance of global literature
led with an H-index of 30 and over 3,500 total citations,
Based on the established search criteria, a total of reflecting its dominant research output. China followed
311 publications were retrieved, covering the period with an H-index of 18 but had a lower total citation count,

Volume 1 Issue 3 (2025) 3 doi: 10.36922/or.8295