Page 112 - GHES-3-2

Global Health Economics and
Sustainability

ORIGINAL RESEARCH ARTICLE
Hospitalizations, deaths, and health costs for

diabetes mellitus and obesity in Acre, Brazil: A
retrospective time-series study (2000 – 2021)

Jorgimar Peres Ferreira 1,2 , Mauro José de Deus Morais * ,
1,2
Francisco Naildo Cardoso Leitão 1,2 , Thaiany Pedrozo Campos Antunes 3 ,
Douglas Silva de Oliveira 1,2 , Luiz Carlos de Abreu 3 , and
Romeu Paulo Martins Silva 4
1 Center for Health Sciences and Sports, Federal University of Acre, Rio Branco, Acre, Brazil
2 Multidisciplinary Laboratory of Studies and Scientific Writing in Health Sciences - LaMEECCS,
Center for Health Sciences and Sports, Federal University of Acre, Rio Branco, Acre, Brazil
3 Laboratory of Scientific Writing, School of Sciences of Santa Casa de Misericórdia (EMESCAM),
Vitória/Espírito Santo, Brazil
4 Special Academic Biotechnology Unit, Federal University of Goiás, Catalão, Goiás, Brazil

Academic editor: Abstract
Mihajlo Jakovljevic M.D. Ph.D. MAE
Introduction: Obesity and type 2 diabetes mellitus (T2DM) are among the most
*Corresponding author:
Mauro José de deus Morais significant public health challenges worldwide, with profound effects on morbidity,
(mauro.morais@ufac.br) mortality rates, and healthcare costs. Objective: The aim of this study is to evaluate
Citation: Ferreira, J.P., the trends in deaths, hospitalizations, and hospital costs associated with T2DM and
Morais, M.J.D., Leitão, F.N.C., obesity in Acre, Brazil, from 2000 to 2021. Method: This retrospective time-series
Antunes, T.P.C., de Oliveira, D.S., study utilized official microdata from the Mortality Information System, the Hospital
de Abreu, L.C., et al. (2025).
Hospitalizations, deaths, and Information System (SIH/SUS), and the Information System for Notifiable Diseases, all
health costs for diabetes mellitus registered with the Ministry of Health through the SUS Department of Informatics.
and obesity in Acre, Brazil: Data were extracted for T2DM cases between 2000 and 2021, and for obesity cases
A retrospective time-series study
(2000 – 2021). Global Health Econ from 2013 to 2021, focusing on age, sex, and race/skin color, as well as death rates,
Sustain, 3(2):104-112. hospitalizations, hospital costs, and municipality-level variations. Results: Our
https://doi.org/10.36922/ghes.3027 findings reveal a significant increase in T2DM-related deaths over the study period,
Received: February 27, 2024 accompanied by rising hospital costs. A higher prevalence of T2DM-related mortality
was observed among older age groups, with a roughly equal distribution between
Revised: November 21, 2024
men and women. For obesity, hospitalizations were more frequent after the age of
Accepted: December 5, 2024 30, particularly among women. In addition, a strong correlation was found between
Published online: December 31, deaths from T2DM and hospitalizations due to obesity, suggesting that many T2DM-
2024 related deaths occurred among individuals also hospitalized for obesity, a condition
Copyright: © 2024 Author(s). that often involves multiple comorbidities.
This is an Open Access article
distributed under the terms of the
Creative Commons Attribution Keywords: Deaths; Hospitalization; Diabetes; Obesity
License, permitting distribution,
and reproduction in any medium,
provided the original work is
properly cited.
1. Introduction
Publisher’s Note: AccScience
Publishing remains neutral with Obesity and type 2 diabetes mellitus (T2DM) are among the most significant global
regard to jurisdictional claims in
published maps and institutional public health challenges, with considerable impacts on morbidity, mortality, and
affiliations. healthcare costs (Whiting et al., 2011; Wild et al., 2004). These diseases are classified as

Volume 3 Issue 2 (2025) 104 https://doi.org/10.36922/ghes.3027