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Gene & Protein in Disease FXR1 modulates gene expression in cancer

Score 0.93541616 0.51442057 0.6119528 0.52791125 0.55741394 0.530119 0.6568217 0.5021565 0.9143031 0.52305186 0.5148203 0.9388821 0.936801 0.5166229 0.51078486 0.5004961 0.54091585 0.540495 0.5815808 0.51607025 0.9999931

CUCUUUGGCUGGCCUUCACUAGUGUUUGUCUUCAAGAAUGAAGAUUACUUUAAGGAUCUGUGUGGACCAG
AGUGGCUGAAUUGGAAAUGAUAAAAUAAAAUGAAAUUUUAGGAGCUCGCUGGCUGGGACAGGCCUGGACU
AGCUUCUUUAUGAAAAAGGCAUCAGCCUCAGGGCCUCCUUCAUCUUCAUCUCUGUCUGCAGUACCUGGCA
AACAAACGAUUGAGGCAGGAUUUGGAUAUUGCUCUACAUGACGGGAAAGCCUGUGCUCUUGGAAUUACAG
UCAUUACAGUCUACAGAAUGAAAGAGUAACCUGUCCCAGAGGAGAGGCAGGUGAAAGACUCCACAGCAUG
GCCAUGUCGGCCCUCAGCCUCCUCAUUCUGGGCCUGCUCACGGCAGUGCCACCUGCCAGCUGUCAGCAA

GGCCUGGGGAACCUUCAGCCCUGGAUGCAGGG
CAGGUCCAGUGAGCAUGAGAAUGCCUAUGAG CCGUCGGAAACAAGGCAGAUGGAGUCCUGGUGGGAACAGAUGGAAGGUACUCUUCGAUGGCGGCCAGUUU AGAGGGGAGCACGUGCCCCCUGCAUCCAUUCUCUCUUUCUCUUGAUGACGCAGCUGUCAUUUGGCUGUGC UAGAGAUUUAGUCUUAAUUUCAACCAAAUGACAUGCAAGAUUCCACUGCCACUCUUCCUGGCCAAAAGUG ACUCAUCUACAGGAAUUAAAUGGAAAAAACAGGCUAGGAUUUCUCAGCACACUUUAGGAGUGAAUGAAAA GAAACAACGACAAGCCAGACUGGAAUAUGAAUGGGACCUGGUGGACUUUGAAGAGGAACAGCAGCAGCUU UCCUGAGGAACUUGAUAGACAAACAAUGACAGUGUUUUCCAG

Table 2. The score of FXR1 binding site on different genes

Sequence NA NA NA Note: The sequence highlighted in red indicates the FXR1 potential binding site in the target mRNAs.

Accession no. NM_001099294.2 NM_0012782062 lncRNA gene NM_005764.4 NM_0203113 NM_0012040872 NM_001329749.2 NM_2135993 NM_0032827.7 NM_0015533 NM_213599.3 NM_0010015525 NM_0011953823 NM_0046254 NM_0039504 Abbreviations: lncRNA: Long non-coding RNA; NA: Not available.

Sequence name SHISAL1 SLC43A3 NBAT1 PDZK1IP1 ACKR3 KCNN3 NECAB2 ANO5 ATOH8 IGFBP7 ANO5 LEMD1 GPR35 WNT7A F2RL3

Volume 4 Issue 1 (2025) 9 doi: 10.36922/gpd.5068