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Global Translational Medicine                                      A Taxonomy of AI Assisted Medical Robots



            configuration to reduce the trade-off between size and   the robotic manipulation arms and the endoscopy into one
            power, reflecting their comprehensive efforts toward   trocar through the abdominal wall.
            the exploration of NOTES. The navigation of NOTES    The difficulties in using single port-laparoscopic
            robots within the lumen would be a topic of interest   robots lie in the solvability and theoretical formula
            considering the synthesis of multiple AI technologies,   derivation of multi-arm single-port surgical coordinates
            such as visual semantic segmentation and recognition,   trajectory mapping. As we know, the singularities of
            inertial information fusing, and so on. The integration   artificial intelligence-assisted robotic arms with a confined
            of NOTES and soft-bodied robots would be another   workspace are major issues. Notable innovative single-
            technical direction, as conventional NOTES tends to cause   port laparoscopic robot prototypes have been proposed
            injuries and discomfort to the natural orifices of the body.   over the past 5 years [67,68] . Bai et al. proposed an optimized
            The soft-bodies design adjusts the integral positions and   anthropomorphic coordinated control approach through
            speed based on the pressure to the orifice. Hence, the   dual-step optimization based on the dexterous arms in
            tactile sensing technique plays a crucial role for the further   human boxing maneuvers . Bai’s method has shown to
                                                                                    [67]
            development of NOTES.                              achieve higher efficiency and less invasiveness apart from
            2.2.3. Robots for retinal surgery                  addressing the issue of control. Wang  et al. designed a
                                                               comprehensive system, made up of three 6-DoF robotic
            The innovation of AI-ART robots for retinal surgery   arms and a camera-mounted endoscopy, which could be
            predominantly aims at reducing the risk of injury to   inserted into the abdominal cavity through one trocar
            the crystalline lens, corneal injury, and retinal tearing,   with diameter <20  mm. Bai  et al. attempted to address
            all of which may lead to serious consequences and pose   the miniaturization of laparoscopic robots and the
            a challenge for surgeons [63,66] . The additional benefit of   sophisticated control of robotic arms .
                                                                                            [67]
            AI-ART robots for retinal surgery lies in the increased
            dexterity and lower incidence of ocular hypotony. In the   2.3. Medical wearable robots
            treatment of retinal vein occlusion, severe visual loss may   Medical wearable robots are primarily for the improvement
            occur; hence, retinal cannulation of retinal veins using a   of body functionality, including the normal functioning
            smaller-diameter cannula is the best approach thus far.   of internal organs and limb movement. In medical
            Within  the past few  years, there has  been an increasing   therapeutic scenarios, exoskeleton robots generally refer
            interest in ultra-high precision positioning mechanism   to rehabilitation robots. The focus now is on human-robot
            and image segmentation algorithms. In 2021, Jinno    interaction to improve the cognition ability and physical
                                                        [66]
            proposed the use of snake-like robots to address the   assistance provided by robots to humans. Another aspect
            problem of restrained motion within a confined workspace   of medical wearable robots is wearable artificial organs,
            from an appropriate direction, in which multiple surgical   which include microfluidic lung, bioartificial heart,
            tasks were performed on the delicate cornea and retina.   artificial hemodialysis (artificial kidney), artificial liver,
            In 2020, Suzuki  designed a miniature remote center of   and so on [69,70] . The representative medical wearable robots
                         [44]
            motion  manipulator  (RCM)  with  a positional precision   are illustrated in Figure 5.
            of 26.4  mm for teleoperated microsurgery. Retinal
            surgery robots  continue to be  the  best  assistance  for   2.3.1. Assisted chronic disease management
            surgeons. Considering the complexity of retinal surgery,   Compared with wearable nanosensors for medical signal
            automated robots can contribute from three perspectives:   collection, AI-ART for chronic disease management
            (1) Understanding the current semantic processing; (2)   mainly focuses on stage distinction and leveraging more
            learning the control patterns or rules based on the semantic   powerful artificial intelligent algorithms to support the
            process; (3) conducting semantic processing when the   decision-making process. For instance, patients with
            surgeon requires.                                  chronic lymphocytic leukemia (CLL), which is a type of
                                                               cancer that originates from the lymphocytes in the bone
            2.2.4. Single-port laparoscopy                     marrow and spreads to the blood, causing infections and
            A standard laparoscopy surgical robot usually consists of   lowering the immunity, may endure the transformation
            3–4 ports to supply accesses for the robotic arms, including   into the next stage: Aggressive malignant lymphoma.
            several manipulators and one planar or stereo imaging   However,  determining  whether  the  patient  is  in  the
            endoscopy.  Compared  with  manual  open  procedures  of   first  stage  or  second  stage  is  challenging  due  to  limited
            standard specifications, the standard laparoscopy surgical   guidelines and insufficient morphologic experience of
            robot can effectively reduce the invasiveness of surgery. The   biopsy specimens. Therefore, researchers from University
            incision is small as single-port laparoscopy robot integrates   of Rochester Medical Center, Rochester and University of


            Volume 1 Issue 2 (2022)                         6                      https://doi.org/10.36922/gtm.v1i2.176
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