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International Journal of Bioprinting                               Mechanically biomimicking 3D bone model


































































            Figure 8. Mimicry of the mechanical properties of natural vertebra via adjustment of infill variation parameters. Adjustment of (A) D , (B) D , and (C) vol   S
                                                                                                     S
                                                                                                H
            for mimicking stiffness and failure load of Female C7, Male C7, and Female T10, respectively (mean± standard deviation; n = 5).

            producing high resistance to subsidence. These results are   bone implants. The compressive deformation behaviors
            consistent with previous studies using FEM simulations   of the artificial vertebrae were similar to those of natural
            and cadaver test results. 45-47                    bones, with the hard part corresponding to the cortical
                                                               bone being preliminarily deformed and the soft part
            4. Conclusion                                      corresponding to the cancellous bone subsequently
            This study demonstrated the potential of 3D-printed   collapsing. We investigated the effect of infill parameters,
            artificial vertebrae with bone-mimicked infill variations,   including the infill densities of the hard and soft regions
            fabricated through MEX, as an effective tool for evaluating   and the volume ratio of the soft region, on the mechanical


            Volume 10 Issue 1 (2024)                       427                          https://doi.org/10.36922/ijb.1067
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