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International Journal of Bioprinting                               Mechanically biomimicking 3D bone model




























            Figure 9. Three-dimensional modeling and printing of patient-specific implant with the conformed interface at the upper surface of Female L4 and Male
            L4 vertebrae. Red boxes indicate the conformed features of the interface.








































            Figure 10. (A) Mimicry of stiffness and failure load of Male L4 natural vertebra by controlling infill parameters of D  and D (mean ± SD and n = 5).

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            (B) Load–displacement curves of natural and artificial vertebra models under implant compression. (C) Load–displacement curves of artificial vertebra
            models compressed by patient-specific (3D printed) and commercial implants. (D) Geometries of implant–vertebra interfaces of commercial and patient-
            specific implants.
            properties of stiffness and failure load under implant   bone models based on CT data of cadavers, we mimicked
            compression. The desired properties  of artificial  bones   the natural vertebrae for both appearance and mechanical
            could  be  achieved  by  optimizing  the  infill  variation   properties. To test the feasibility of the developed artificial
            parameters. By applying the infill variation to 3D-printed   bone model, we fabricated patient-specific implants with

            Volume 10 Issue 1 (2024)                       428                          https://doi.org/10.36922/ijb.1067
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