Page 434 - IJB-10-3

International

Journal of Bioprinting

RESEARCH ARTICLE
Effects of modeling strategies of triply periodic

minimal surface on the mechanical properties
and permeability of biomedical TC4 porous

scaffolds

Binghao Wang 1,2† , Chengliang Yang 1,2† , Chuanchuan Zheng 1,2† , Miao Luo ,
1,2
Zheng Shi , Yuting Lv *, Wen Peng *, and Liqiang Wang *
5,6
3
4
3
1 Affiliated Hospital of Youjiang Medical University for Nationalities, Youjiang Medical University for
Nationalities, Baise, Guangxi, China
2 Guangxi Key Laboratory of Basic and Translational Research of Bone and Joint Degenerative
Diseases, Guangxi Biomedical Materials Engineering Research Center for Bone and Joint
Degenerative Diseases, Guangxi Health Commission Key Laboratory of Clinical Medicine Research
on Bone and Joint Degenerative Diseases Cohort, Guangxi Health Commission Key Laboratory of
Biomedical Materials Research, Baise, Guangxi, China
3 College of Mechanical and Electronic Engineering, Shandong University of Science and
Technology, Qingdao, Shandong, China
4 Orthopedic Implant (Stable) Engineering Technology Research Center, Foshan, Guangdong, China
5 State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University, Shanghai, China
† These authors contributed equally
to this work. 6 National Center for Translational Medicine, Shanghai Jiao Tong University, Shanghai, China
*Corresponding authors: (This article belongs to the Special Issue: Special Issue of International Journal of Bioprinting in the BDMC
Yuting Lv 2023 Conference)
(lyt8608@126.com)
Wen Peng
(pw911210@hotmail.com) Abstract
Liqiang Wang
(Wang_liqiang@sjtu.edu.cn) Modeling strategies play a crucial role in determining the unit shapes of triply periodic
minimal surface (TPMS), significantly affecting the mechanical and permeability
Citation: Wang B, Yang C,
Zheng C, et al. Effects of modeling properties of porous scaffolds. In this study, two distinct strategies including
strategies of triply periodic minimal surface thickening and surface filling were used to construct scaffold models based
surface on the mechanical on four basic TPMS structures (Primitive [P], Gyroid [G], Diamond [D], and I-graph-
properties and permeability of
biomedical TC4 porous scaffolds. wrapped package [IW-P]). These models were successfully prepared using TC4 alloy
Int J Bioprint. 2024;10(3):2565. and selective laser melting technology. Macro/micro morphology, mechanical
doi: 10.36922/ijb.2565 properties, and permeability tests of porous implants were carried out. The results
Received: December 28, 2023 indicate that the scaffolds effectively replicated the designed models, exhibiting
Accepted: February 16, 2024 mechanical properties that match those of human tissue. The elastic modulus
Published Online: March 29, 2024 ranges from 3.03 to 4.57 GPa, and the tensile strength varies between 135.78 and
Copyright: © 2024 Author(s). 250.90 MPa. The surface thickening strategy alters the material distribution within
This is an Open Access article the unit, enhancing load uniformity on the scaffolds, thereby increasing the strength
distributed under the terms of the
Creative Commons Attribution of the scaffolds with G, D, and IW-P units, while reducing stress fluctuations during
License, permitting distribution, compression. In contrast, the surface filling structure exhibits excellent permeability,
and reproduction in any medium, with permeability rates falling within the range of 0.88 to 1.91 × 10 m , aligning with
-9
2
provided the original work is
properly cited. the permeability performance of trabecular bone. This study offers new insights into
the design of porous scaffold models tailored for various application scenarios.
Publisher’s Note: AccScience
Publishing remains neutral with
regard to jurisdictional claims in
published maps and institutional Keywords: Porous scaffolds; Triply periodic minimal surface; Mechanical
affiliations. performance; Modeling strategies

Volume 10 Issue 3 (2024) 426 doi: 10.36922/ijb.2565