Page 439 - IJB-10-3
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International Journal of Bioprinting                                  Different modeling of porous scaffolds




            Table 2. Parameters in the formula for calculating permeability  Table 3. Parameters of the scaffolds
             Symbol  Parameter                  Value                       Design    Design surface    Actual
                                                                          porosity (%)  area (mm )  porosity (%)
                                                                                              2
                                                 −3
             Μ      Dynamic viscosity coefficient of water  10 Pa∙s
             H      Height of samples           18 mm           P-F           60          1831        61.95
             A      The cross-sectional area of the water   490.625 mm 2  P-T  60         3293        63.39
                    column                                      G-F           60          2416        60.09
             A      The cross-sectional area of the scaffold  113.04 mm 2  G-T  60        4220        60.95
                                                 3
             Ρ      Density of water            10  kg/m 3      D-F           60          2860        61.84
             G      Gravity acceleration        9.8 m/s 2       D-T           60          5287        62.29
                                                                IW-P-F        60          2617        62.01
            images,  it  can  be  observed  that  the  porous  structures   IW-P-T  60    4933        62.62
            between  different  scaffolds  are  well-constructed,  and   Abbreviations: D, Diamond; F, Fill; G, Gyroid; IW-P, I-graph-wrapped
            there are no apparent blockages in the porous scaffolds.   package; P, Primitive; T, Thicken.
            Interconnected  porous networks  have been shown to
            promote inward bone growth.  Table 3 shows the design   the data reveals a discernible pattern  in the impact of
                                    35
            parameters and measured porosities among different   structural units and modeling strategies on scaffold
            porous scaffolds. It is evident that there is a difference   porosity. It is evident that the porosity of the scaffolds
            between the designed porosity and the porosity measured   consistently increased, indicating material reduction
            using the drainage method, with the printed scaffold’s   during processing. This reduction is primarily attributed to
            porosity being higher than the design value. However,   the step effect inherent in the printing process, particularly
            the overall error in the scaffolds is approximately 2%,   when there are substantial changes in the surface angles,
            indicating a certain degree of repeatability in the additive   resulting  in  material  reduction  at  the  scaffold  edges.
            manufacturing of porous scaffolds.
                                                               Notably, the porosity of the thickened minimum surface
               Table  3  presents  the  design  parameters  and  actual   scaffold is significantly higher than that of the equivalent
            porosity of the scaffold. A more in-depth analysis of   surface-filled scaffold across different modeling strategies.



































            Figure 4. (A) Appearance of the scaffold under optical microscopy. (B) Scaffold’s image captured with micro-CT. Abbreviations: D, Diamond; F, Fill; G,
            Gyroid; IW-P, I-graph-wrapped package; P, Primitive; T, Thicken.


            Volume 10 Issue 3 (2024)                       431                                doi: 10.36922/ijb.2565
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