Page 612 - IJB-10-3

International

Journal of Bioprinting

RESEARCH ARTICLE
Early monitoring for 3D-printed patient-specific

mandible reconstructive implant biomechanical
behavior under different occlusal conditions

using a wireless module system

Cheng-Hsien Wu , Hsiao-Kuan Wu , Pei-Jung Tsai , and Chun-Li Lin *
4
5
1,2
3
1 Oral & Maxillofacial Surgery, Department of Dentistry, Taipei Veterans General Hospital, Taipei,
Taiwan
2 Department of Dentistry, School of Dentistry, National Yang Ming Chiao Tung University, Taipei,
Taiwan
3
Department of Exercise and Health Science, National Taipei University Nursing and Health
Sciences, Taipei, Taiwan
4 Department of Biomedical Engineering, National Yang Ming Chiao Tung University, Taipei, Taiwan
5 Department of Biomedical Engineering, Medical Device Innovation & Translation Center, National
Yang Ming Chiao Tung University, Hsinchu, Taiwan

Abstract

Three-dimensional (3D) printing technology used to manufacture patient-specific,
large-scale medical implants has become increasingly prevalent. Nevertheless, early
biomechanics monitoring can enhance the implantation success rate. This study
*Corresponding author: developed a wireless module system (WMS) for strain gauge measurement that can
Chun-Li Lin (cllin2@nycu.edu.tw) be placed within the implant to achieve early biomechanical behavior detection for
an experimental 3D-printed metal model of a patient-specific segmental implant
Citation: Wu CH, Wu HK,
Tsai PJ, Lin CL. Early monitoring (MMPSI) after surgery. This WMS includes a chip, a circuit board, and a battery, all with
for 3D-printed patient-specific dimensions smaller than 20 mm × 12 mm × 8 mm. This system can connect to strain
mandible reconstructive implant gauges and interface with a mobile application for measuring and transmitting strain
biomechanical behavior under
different occlusal conditions using a data. The WMS functionality was confirmed through cantilever beam experiments.
wireless module system. Premature failure was detected using this WMS installed in an experimental
Int J Bioprint. 2024;10(3):2553. 3D-printed MMPSI and through in vitro fatigue biomechanical testing under
doi: 10.36922/ijb.2553 different occlusal forces applied on the plastic-simulated mandibular model. The
Received: December 27, 2023 WMS validation results indicated that the strain gauge measurement error compared
Accepted: February 19, 2024 to theoretical values was within 17%. Biomechanical fatigue results addressed the
Published Online: March 25, 2024 higher strain received and greater cyclic loads were recorded when occlusal force
Copyright: © 2024 Author(s). was applied onto the premolar under identical force application conditions because
This is an Open Access article the premolar was closer to the strain gauge attachment location, resulting in a longer
distributed under the terms of the
Creative Commons Attribution lever arm compared to the molar. This study concluded that the developed WMS for
License, permitting distribution, strain measurement can be installed in a patient-specific 3D-printed implant with
and reproduction in any medium, enough internal space to detect early biomechanical behavior after surgery. Current
provided the original work is
properly cited. results of in vitro fatigue test for segmental defect indicated that occlusal situation
can be adjusted to reduce implantation failure risk.
Publisher’s Note: AccScience
Publishing remains neutral with
regard to jurisdictional claims in
published maps and institutional Keywords: 3D-printed implant; Wireless; Biomechanics; Patient-specific;
affiliations. Mandibular defect

Volume 10 Issue 3 (2024) 604 doi: 10.36922/ijb.2553