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International Journal of Bioprinting                                 Structural design of D-surface scaffolds




            (B) formation, and mild edema (E) were observed among   bioactivity factors to foster an early-stage conducive 3D
            the three groups of bone cortex.  It was noticeable that   microenvironment for osteoblasts.
                                       34
            the PBAT/PLA+PRP scaffold has a much higher degree of
            bone generation than those in the PBAT/PLA and control   Rabbit femurs with the PBAT/PLA+PRP scaffold were
            scaffolds. Overall, the in vitro study results indicated that   monitored and scanned by a clinical CT at 1, 2, and 4 weeks after
            the D-surface scaffold groups have sufficient surface area   implantation. The scanned sliced images were collected and
            for cell attachment, migration, and proliferation. The   reconstituted. By using the volume rendering technique and
            PRP-loaded scaffolds have demonstrated the release of   multi-planner reformation technique, the bone parameter






























































            Figure 12. Clinical computed tomography (CT) scanning of the experimental rabbit, and the reconstituted images based on (a) volume rendering
            technique (VRT) and (b and c) multi-planner reformation (MPR) from different views. (d) The poly(butylene adipate-co-terephthalate)/poly(lactic
            acid) with platelet-rich plasma (PBAT/PLA+PRP) scaffold implanted in the rabbit femur, and the reconstituted images scanned by micro-CT 4 weeks
            after implantation.


            Volume 10 Issue 5 (2024)                       194                                doi: 10.36922/ijb.3416
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