Page 423 - IJB-9-2

International Journal of Bioprinting Design and 3D printing of TPMS breast scaffolds

A B

C D

E F

G H

Figure 4. The optimization of triply periodic minimal surface (TPMS) scaffold: (A) Four TPMS scaffolds with different relative density; (B) the mechanical
properties of scaffolds with different relative density; (C) the design of multiple parallel channels penetrating through scaffold; (D) the mechanical
properties of scaffolds with different channel diameter; (E) the flow velocity distribution in the optimized scaffold; (F) the fluid velocity fluctuation of
the optimized scaffold; (G) the pressure drop in the optimized scaffold; and (H) the permeability of the optimized TPMS scaffold loaded with hydrogel.

Therefore, this study improved the structure on the basis were also assessed by the compression model mentioned
of Gyr-15 by designing multiple parallel (3 × 4) channels before. The results (Figure 4D) showed that the elastic
through the scaffold (Figure 4C) in three directions with modulus of the scaffold was significantly reduced by
a distance of 5 mm between parallel channels. To explore adding channels. The elastic moduli of Gyr-2.6, Gyr-2.8,
the influence of different channel diameters on the and Gyr-3.0 were all below the target (1 MPa), which
mechanical performance of the scaffold, Gyroid scaffolds were 0., 0.44 MPa and 0.19 MPa, respectively. The average
with six channel diameters of 2.0 mm, 2.2 mm, 2.4 mm, stress of the scaffold under load gradually increases with
2.6 mm, 2.8 mm, and 3.0 mm were designed and named the increase of the channel diameter. However, the stress
Gyr-2.0, Gyr-2.2, Gyr-2.4, Gyr-2.6, Gyr-2.8, and Gyr-3.0, increases slowly between 2.2 and 2.6 mm and rapidly
respectively. The mechanical properties of these scaffolds between 2.6 and 3.0 mm, and the stress value at 3.0 mm is

Volume 9 Issue 2 (2023) 415 https://doi.org/10.18063/ijb.685