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International Journal of Bioprinting Bioprinting in wound dressing and healing

Figure 9. Keywords confusion matrix for bioprinting in wound dressing and healing.

(ii) Based on the category’s analysis, it can be concluded gelatin, fibrinogen, etc.) and polysaccharides (e.g.,
that developments in materials science, especially chitosan, alginate, etc.). Synthetic biopolymers
innovations in polymeric materials, are significant are artificial polymers, including polylactic acid,
for this topic. Biomaterials are essential to ensure polyglycolic acid, polycaprolactone, etc. Synthetic
the viability and responsiveness of cells in the biopolymers have excellent mechanical properties
printed architecture. It must be biocompatible, and can adapt mechanical properties and degradation
biodegradable, printable, biologically inert, strong, characteristics to skin grafts by modifying the
durable, and malleable. For example, the hydrogel polymer structure.
is one of the most commonly used materials to
be printed. However, traditional hydrogels have (iv) There is a strong interest in this topic from countries
some detrimental properties to wound dressing other than South America and Africa. The USA,
and healing, such as poor physical properties. China, Spain, England, and India contributed the most
These properties can be improved by compounding significant number of papers on this topic. Since the
hydrogels with other materials. research on this topic is in a very hot state, researchers
from some new countries would contribute papers
(iii) The most common type of material used is polymers. to this field every year. More countries joining the
They can be divided into natural and synthetic research on this topic is to be expected.
polymers according to their production sources.
Natural biopolymers are naturally occurring (v) This topic has resulted in an influential collaborative
biopolymers, including proteins (e.g., collagen, network. This cooperative network was mainly led by

Volume 9 Issue 2 (2023) 61 http://doi.org/10.18063/ijb.v9i2.653