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International Journal of Bioprinting                           Comparison of different 3D printing technologies



                                                               Table 3. Results of the printability study
                                                                Hydrogel  Image                  Pr  State of
                                                                                                    gelation
                                                                CELLINK                          1  Appropriate
                                                                Start











                                                                5% HaMA                          <1  Low








                                                                5% GelMA                         1  Appropriate/
                                                                                                    High
             Figure 7. Comparative study of printability. Source: own elaboration.







                                                                Matrigel                         <1  Low












                                                               biodegradation  characteristics.  This  last  characteristic  is
                                                               very  interesting for  the  objectives proposed,  as it would
                                                               allow our biomimetic scaffold to biodegrade as bone
                                                               regeneration takes place. In addition, PCL has been shown
            Figure 8. Matrix formed by squares and rectangles of different dimen-  to enhance and promote bone regeneration .
                                                                                                 [36]
            sions. Image obtained using Inventor software. Source: own elaboration.
                                                                  In order to check the suitability of PCL for bioprinting
            could not be correctly performed. The difference   and to see the significant differences with respect to
            between  the  theoretical  value  and  the  real  value  in  the   hydrogels, the above-mentioned tests were used. The only
            area measurements is due, in most cases, to the fact that   test that was not used is the sessile drop method, which does
            the hydrogel did not achieve perfect 90° angles and that   not provide any relevant information on thermoplastics.
            at some points several layers of hydrogel overlapped,
            generating small overflows.                           Table 5  shows the results of the  PCL printing grid
                                                               test, where it can be stated that the previously designed
            3.3. Study of printability of thermoplastics       structure was  reproduced with  practically  no difference
            In this study, we used PCL as a non-toxic thermoplastic   between the theoretical area and the real area. The filament
            because of its good biocompatibility and slow      collapse test shown in Table 6 demonstrates that PCL has


            Volume 9 Issue 3 (2023)                         33                         https://doi.org/10.18063/ijb.680
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