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International Journal of Bioprinting Comparison of different 3D printing technologies

Figure 10. Deformation of the PCL under different applied forces.
thermoplastics in terms of cell viability, which indicates
the ability to introduce cells inside them during the
bioprinting process, they have low mechanical properties
for generating biomimetic structures, either because of
poor gelation that leads to low printability or because they
are unable to generate bridges without collapsing.
Only 5% GelMa allowed the realization of complex
structures to be considered, as it passed all the tests
proposed in this study. After bioprinting a tooth-shaped
structure, it was found that it has high capacity to reproduce
structures without causing problems during printing, but
the 3D shape of the structure generated would change
when forces are applied on it.
PCL, due to its high printability, its high strength, its
ability to produce bridges without collapsing, and its ideal
Figure 11. Tooth printed with PCL.
biological characteristics, is the most interesting of all the
PCL, on the other hand, shows very acceptable materials studied. On the other hand, it should be noted
compression results, as shown in Figure 10. Thus, hardness that 3D bioprinting, in combination with hybrid hydrogels,
characteristics are not a problem of this material, which presents a greater capacity for evolution and a high potential
has negligible deformation when a range of pressures were in tissue engineering, and should therefore be the focus of
applied. our efforts to develop this methodology. Furthermore, the
use of hydrogels provides good cell viability properties by
Figure 11 shows the PCL-printed tooth after better mimicking the extracellular matrix of the different
compression study. tissues of the body, so their improvement and development
should be a priority in the study of bioprinting.
4. Conclusions
In conclusion, of all the materials used in this study, PCL Acknowledgments
and 5% GelMA are valid for the proposed methodology
and for the manufacture of a scaffold with a biomimetic We want to thank the European Regional Development
shape. Although the hydrogels studied are better than Fund (ERDF) under the Interreg V A Spain - Portugal

Volume 9 Issue 3 (2023) 35 https://doi.org/10.18063/ijb.680