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International Journal of Bioprinting                                     Using droplet jetting for bioprinting





















































            Figure 2. Schematic for droplet formation from inkjet with respect to viscoelasticity of the fluid. (a) and (b) are the ejection and stretching of the droplets
            which is common to all fluids. (c) to (i) is the breakup of droplet from Newtonian fluid. (j) to (m) is non-Newtonian fluid with intermediate viscoelasticity.
            (n) to (q) is non-Newtonian fluid with high viscoelasticity. Reprinted with permission from  . Copyright (2010), The Society of Rheology.
                                                                      [49]
            significantly affect filament thinning, break-up time, and   can be broadly categorized based on the two types of
            droplet speed, hence minimizing formation of satellite   substrates  above. Droplets  striking solid surfaces  can
            droplets . A bioink with a slow filament elongation and   bounce, spread, and splash, whereas droplets impacting on
                  [53]
            long rupture time has slower droplet velocity .    liquid surfaces can be seen to bounce, coalesce, and splash.
                                               [54]
                                                               The following section discusses the phenomena based on
               Pneumatic systems are used in microvalve bioprinting
            to make it easier to print materials with higher viscosity so   the outcome of impact, nonpenetrative versus penetrative
                                                               (Figure 3), and the use of droplets to fabricate substrates
                                                        [55]
            that tear-off speed for droplet formation can be reached .   with heterogeneous wettability.
            In other jetting system setup, such as the nozzle-free LIFT,
            the vapor bubble dynamic is influenced by rheological
            characteristics, such as surface tension and viscosity [31-33] .   3. Droplet–substrate interaction
            The vaporization rate is slower for a substance with higher   3.1. Droplet impacting into penetrative substrate
            viscosity, thus reduces the jet velocity.
                                                               Neumann’s law establishes the contact angle between a
               The droplet enters the impact phase upon interaction   liquid surface drop and a droplet in a quasistatic or steady
            with receiving substrate. Droplet impact on solid and   state [61,62] . The relative difference in surface tension between
            liquid substrates has been well studied and the phenomena   the droplet and the pool determines the flow pattern and


            Volume 9 Issue 5 (2023)                        194                         https://doi.org/10.18063/ijb.758
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