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Collocation method with flood-based metaheuristic optimizer for optimal control ...

                             10 6                                  10 6
                                             Without optimal control      With twofold optimal control u ,u *
                                                                                      *
                           11                                                         1  2
                                                                 10
                           10
                                                                 8
                           9
                           S  8                                  S  6
                           7
                                                                 4
                           6
                                                                 2
                           5
                            0    100   200  300   400  500        0    100   200  300   400  500
                                        Time (days)                           Time (days)
                          (a 1 ) Susceptible people under no control.  (a 2 ) Susceptible people under optimal control.
                              7                                     7
                             10                                    10
                                                                 3.6
                           2.9
                                                                 3.4
                           2.8
                                                                                      *
                                                                 3.2      With twofold optimal control u ,u *
                                                                                      1  2
                          V  2.7             Without optimal control  V
                                                                 3
                           2.6                                   2.8
                                                                 2.6
                           2.5
                            0    100   200  300   400  500        0    100   200  300   400  500
                                        Time (days)                           Time (days)
                          (b 1 ) Vaccinated people under no control.  (b 2 ) Vaccinated people under optimal control.
                              4
                             10
                                                                                      *
                                             Without optimal control      With twofold optimal control u ,u *
                           8                                    5000                  1  2
                                                                4000
                           6
                                                                3000
                           I c                                 I c
                           4
                                                                2000
                           2                                    1000
                                                                 0
                            0    100   200  300   400  500        0    100   200  300   400  500
                                        Time (days)                           Time (days)
                         (c 1 ) Infected population with common strain  (c 2 ) Infected population with common strain
                                   under no control.                   under optimal control.
                                                                                      *
                          2500               Without optimal control  150  With twofold optimal control u ,u *
                                                                                      1  2
                          2000
                                                                100
                          1500
                         I v                                    I v
                          1000
                                                                 50
                          500
                                                                 0
                            0    100   200  300   400  500        0    100   200  300   400  500
                                        Time (days)                           Time (days)
                         (d 1 ) Infected population with amplified strain  (d 2 ) Infected population with amplified strain
                                   under no control.                   under optimal control.
                             10 6                                  10 5
                                                                 9.5
                           2.5
                                                                9.48
                                             Without optimal control  9.46
                           2
                          R                                     R
                                                                9.44
                                                                9.42
                           1.5
                                                                 9.4
                                                                                      *
                                                                          With twofold optimal control u ,u *
                           1                                    9.38                  1  2
                            0    100   200  300   400  500        0    100   200  300   400  500
                                        Time (days)                           Time (days)
                           (e 1 ) Recovered people under no control.  (e 2 ) Recovered people under optimal control.
                                                         ∗
                                                      ∗
            Figure 4. Effects of twofold optimal control u , u on various population groups over the time period [0, 500]
                                                      1  2



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