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Innovative Medicines & Omics                                         Antioxidant nanomedicines for therapies




            Table 7. Summary of the representative antioxidant nanomedicines for the treatment of ocular diseases
            Antioxidant nanomedicine                     Reaction type      Disease                   References
            Poly (catechin)-containing nanomedicine      Non-catalytic      AMD                         362
            Resveratrol-loading polycaprolactone nanoparticle  Non-catalytic  AMD                       363
            CeO  nanoparticle                            Catalytic          AMD                        364-366
               2
            Melanin nanoparticle                         Non-catalytic      AMD                         369
            Pt nanoparticle-loading liposome             Catalytic          Retinal neovascularization  379
            Single-atom iron nanocatalyst with defective Fe–N  sites  Catalytic  Retinal neovascularization  380
                                            4
            Chitosan-modified CeO  nanoparticle          Catalytic          Glaucoma                    386
                            2
            Abbreviation: AMD: Age-related macular degeneration




















































            Figure 25. Schematic illustration for the construction of single-atom iron nanocatalyst with defective Fe–N  sites, as well as its application in treating
                                                                                  4
            retinal neovascularization. Reproduced with permission from Zhang et al.  Copyright © 2022, Wiley-VCH.
                                                           380
            and adalimumab have been applied in clinic for treating   cannot scavenge ROS, and their side effects are prominent.
            inflammatory  bowel  disease; 393,394  however, these drugs   Antioxidants such as Vitamin C, Vitamin E, and coenzyme



            Volume 1 Issue 1 (2024)                         32                               doi: 10.36922/imo.2527
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