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Innovative Medicines & Omics Antioxidant nanomedicines for therapies

Figure 28. Scheme for the application of H-silicene nanosheet-integrated EcN in the synergistic therapy of inflammatory bowel disease. Reproduced with
permission from Zhu et al. Copyright © 2022, Wiley-VCH.
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A B

Figure 29. Construction (A) and antioxidation mechanism (B) of single-atom nanocatalyst-integrated probiotic system. Reproduced with permission
from Cao et al. Copyright © 2023, Nature Publishing Group.
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were restored after oral administration, as demonstrated in and antioxidative nanomedicines need to be investigated
murine and canine models. in detail.
Inflammatory bowel disease is a typical disease 11. Skin disease treatment
model for evaluating the anti-inflammatory efficacies
of antioxidant nanomedicines (Table 8). It is noted that The skin is composed of epidermis and dermis, and
during the treatment, the absorption of nanoparticles by stratum corneum at the outmost layer of epidermis acts
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intestinal circulation system should be circumvented. as a barrier to pathogen invasion. For treating skin
Therefore, the interaction between gastrointestinal barrier disease, topical administration is the most efficient way to

Volume 1 Issue 1 (2024) 35 doi: 10.36922/imo.2527