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Microbes & Immunity                                                  Statistical modeling of COVID-19 trends




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            Figure 8. Diagnostic residual plots and correlation analysis of model predictors. (A) Residual plots and (B) scatterplot matrix.
            Note: Asterisks (*) indicate levels of statistical significance: p<0.05 (*), p<0.01 (**), and p<0.001 (***).
            Abbreviations: GDP: Gross domestic product; HDI: Human development index.

              To address these issues, stepwise regression was   Although the resulting model was more manageable,
            employed as an initial strategy to reduce model complexity   notable multicollinearity persisted, with several VIF values
            by removing less  significant predictors.  The  simplified   remaining high, albeit reduced from their initial levels.
            model retained key variables and interaction terms that
            contributed meaningfully to the model’s explanatory   To further address the issue of multicollinearity,
            power while excluding those with minimal impact.   alternative approaches such as PLS and PCR were


            Volume 2 Issue 3 (2025)                        123                           doi: 10.36922/MI025040007
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