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Advances in Radiotherapy
            & Nuclear Medicine                                                    OrthoCT experimental proof of concept





















            Figure 7. Macrostructure of the linear accelerator (linac) beam measured with the prototype. Left and middle: persistence graph obtained from 100
            waveforms with different time scales. The period between beam pulses is 4.85 ms. Right: impulse obtained from the average of 100 waveforms.

            field flux significantly diminishes the signal-to-noise ratio,
            potentially compromising the ability to detect the signal of
            interest originating from radiation scattered on the target.
            Eliminating the background escaping the linac head poses
            a challenge. However, its impact on the detector can be
            mitigated by the introduction of shielding material.  To
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            this end, several blocks of Cerrobend and lead (with a
            density of 9.38 g/cm  and 11.34 g/cm , respectively) were
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                            3
            positioned around the detector. Various configurations
            were tested, and the one yielding the best results is
            illustrated in Figure 8. Approximately 315 kg of shielding
            material was used.

              To analyze the influence of the shielding on the
            performance of the prototype, preliminary measurements
            were conducted in the linac room. Figure 9 shows the dose   Figure  8. Views from different angles of the shielding configuration
            equivalent values measured with the AT1123 dosimeter   employed to mitigate the out-of-field radiation escaping from the linear
            (ATOMTEX, Minsk, Republic of Belarus) at various   accelerator (linac) head.
            positions of the prototype after the positioning of the
            shielding material. Upon analysis of the values, it is evident
            that the shielding configuration employed significantly
            reduces the impact of background radiation on the system.
            The  comparison  of  the values  measured  at positions  A
            and D reveals a reduction in background by a factor of
            approximately 250. Figure 10 displays the spectra obtained
            with (blue) and without (red) a polymethylmethacrylate
            (PMMA) target positioned in front of the detector, using
            different geometric configurations of the shielding material
            placement. As illustrated, inadequate shielding leads to the
            masking of the target signal (left), with <30 bins of variation
            between the two spectra. Improved shielding enhances the
            ability to detect the target (right), increasing the difference
            to approximately 270 bins
            2.5. Experimental procedure

            Figure 11 illustrates the experimental setup implemented in   Figure 9. Dose equivalent values were measured at various positions of
                                                               the prototype system. The comparison of the values measured at positions
            the radiotherapy environment, including the experimental   A and D reveals a reduction in background influence by a factor of
            phantom and the linac head. The prototype was positioned   approximately 250.



            Volume 2 Issue 3 (2024)                         6                              doi: 10.36922/arnm.4099
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