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Brain & Heart                                                          Pictorial rendition pulmonary stenosis


























            Figure 33. The changes in precordial voltages among patients in Group I   Figure  35. The relationship between post-balloon pulmonary
            and Group  II following balloon pulmonary valvuloplasty (BPV). In   valvuloplasty (BPV) electrocardiograms (ECGs) and post-BPV peak
            Group  I, there was a significant reduction (P  < 0.05 – 0.01) in right   gradients across the pulmonary valve. ECGs appear normal in patients
            ventricular voltages, as reflected by R waves in V3R and V1 and S waves in   with peak gradients across the pulmonary valve lower than 30 mmHg
            V6 (left group). Conversely, in Group II patients, there was no substantial   at follow-up (left group; filled circles). Conversely, hypertrophied right
            change (P > 0.1) (right group).                    ventricle (RVH) was observed in patients with residual pulmonary valve
            Abbreviation: SD: Standard deviation. Amended from Rao. 48  gradients >30 mmHg (right group; filled circles) or when the ECG was
                                                               recorded <6 months after BPV (right group; open circles). In the latter
                                                               group, despite peak gradients across the pulmonary valve being lower
                                                               than 30 mmHg, it is inferred that RVH does not regress within 6 months
                                                               following BPV.
                                                               Abbreviations: m: Mean; SEM: Standard error of the mean. Reproduced
                                                               from Rao. 48
















            Figure  34. The time course of changes in precordial voltages among
            Group I patients following balloon pulmonary valvuloplasty (BPV). The
            right ventricular voltages, as reflected by R waves in V3R and V1, did not
            show a significant decrease (P > 0.05 – 0.1) in the 3-month follow-up
            electrocardiogram (ECG). However, ECGs at 6 and 12 months post-BPV   Figure  36. The peak instantaneous Doppler gradients across the
            demonstrated a significant reduction (P < 0.05 – 0.001) in these voltages.   pulmonary valve at long-term follow-up (LTFU) were significantly lower
            The data are expressed in mean values. Adopted from Rao. 48
                                                               (P  < 0.001) compared to pre-balloon pulmonary valvuloplasty (BPV)
                                                               (Pre) measurements. These values remained lower (P < 0.01) than those
                                                               immediately after BPV (Post) and those at intermediate-term follow-up
            7  years. Parameters such as residual Doppler pulmonary   (ITFU) Doppler gradients. These data indicate successful relief of
            valve gradients, event-free rates (evaluated using the Kaplan-  pulmonary valve obstruction by BPV at LTFU.
            Meyer  method ),  and  prevalence  of  PI  were  assessed.   Abbreviation: SD: Standard deviation. Amended from Rao et al. 21
                        63
            Doppler data indicated favorable outcomes with low residual
            gradients for the entire cohort (Figure 36). Actuarial rates,   follow-up (Figure  38). The method of PI grading is
            indicating the likelihood of avoiding repeat intervention,   presented in Figure 39.  Despite the increased prevalence of
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            were in the mid-to-high 80s at both 5 and 10 years after   PI, there was no evidence of the right ventricular dilatation
            BPV  (Figure 37). However, PI was observed at long-term   (Figure 40), with only a minimal increase in the incidence
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            Volume 2 Issue 1 (2024)                         11                        https://doi.org/10.36922/bh.2406
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