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International Journal of Bioprinting OLS design for distal femur osseointegration

Figure 9. Relationship between lattice alignment angle/surface area and bone strain.

Figure 10. von Mises stress distribution for 0° and 45° lattice alignment angle.

outcome may be attributed to the porosity and structure Additionally, literature suggests that a lattice porosity
of the lattice. The OLS implant’s surface features flat areas ranging from 60% to 70% is deemed optimal for cell
that offer a favorable environment for initial cell adhesion, growth. In alignment with this, the OLS implant exhibited
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promoting cell stabilization and survival. As cells grow into a porosity of 69.8% in this study. This affirms that, for
the lattice’s internal void, the OLS implant’s varied corner favorable bone growth characteristics, the lattice must not
features facilitate cell clustering, inducing differentiation only undergo mechanical stimulation but also possess a
and proliferation. Consequently, the OLS implant structure conducive to cellular growth. Such attributes
demonstrated superior biological activity compared to the are crucial for facilitating the implant to achieve favorable
smooth disc in in vitro biological tests. osseointegration.

Volume 10 Issue 2 (2024) 557 doi: 10.36922/ijb.2590