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International Journal of Bioprinting                           Sub-regional design of the bionic bone scaffolds




























                                         Figure 10. Bionic bone scaffolds fabricated by LPBF process.
            Table 5. Porosity of the as-designed models and the as-built   (refer to Figure 12b). Meanwhile, Figure 12e depicts that
            specimens                                          the corresponding elastic modulus reaches a value range
                                                               of 1.5–4.52 GPa. Thus, the Gibson–Ashby formula can be
                               Porosity (%)                    rewritten as follows:
             Part number  3D model  LPBF specimen  Deviation (%)
                                                                              Φ
             (01)      67.90       65.33        2.57              S = 1551 18 1.(  −  ) 163.            (VIII)
             (02)      69.88       68.75        1.13                          100
             (03)      69.24       66.93        2.31              E = 20 83 1.(  −  Φ  ) 117.             (IX)
             (04)      70.26       68.45        1.81                        100
             (05)      72.28       69.66        2.62              The increasement of C  and C  leads to a greater porosity.
                                                                                        2
                                                                                   1
             (06)      72.63       70.59        2.04           The diameter of struts decreases accordingly, resulting in
                                                               the decay of stiffness and an easier deformation. Figure 13
             (07)      72.43       71.36        1.07           shows the growth rate diagrams of  E and  S as porosity
             (08)      71.05       69.84        1.21           decreases. In this study, the growth rate is defined as the
             (09)      72.25       70.06        2.19           ratio of ΔS (ΔE) to S  (E ), where the corresponding value
                                                                                  0
                                                                               0
             (10)      66.03       64.97        1.06           of S (E) is determined as S  (E ) when design variable C
                                                                                                             1
                                                                                        0
                                                                                     0
                                                               or C  takes the value of its upper limit. When the porosity
             (11)      59.93       57.27        2.66           is determined only through the variable C  ranging from
                                                                  2
             (12)      54.29       53.18        1.11           60% to 90% with a constant C  = 50% (No. 09, 10, 11, and
                                                                                                 2
                                                                                       1
             (13)      77.89       75.94        1.95           12), the ultimate strength increases by 10% as C  decreases
                                                                                                     2
             (14)      83.36       79.83        3.53           by about 10% (Figure 13a). The growth rate of E is slightly
             (15)      88.59       85.08        3.51           higher than that of  S. Similarly, when the porosity is
                                                               determined  only  through  the  variable  C   ranging  from
                                                                                                 1
            application of Gibson–Ashby model [46,47] , the expressions   50% to 80% with a constant C  = 90% (No. 09, 13, 14, and
                                                                                       2
            can be fitted as follows:                          15), S and E increase significantly with the decrease of C .
                                                                                                            1
                                                               As depicted in Figure 13b, the growth rate of S is almost
                           Φ                                   10 times greater than that in Figure 13a as C  decreases
               S = 375 64 1.(  −  ) 052.               (VI)                                         1
                          100                                  by 10%. Given a certain  C  = 50%, porous biomaterials
                                                                                     1
                                                               in sub-region A have a constant C  value equal to 50%
                                                                                           cell
                          Φ
               E = 16 27 1.(  −  ) 106.               (VII)    and a variable C  value ranging between 60% and 90%. S
                                                                            face
                         100                                   increases as C  decreases, but the amplitude of the change
                                                                          face
               Similarly, the ultimate strength of specimens with   is not significant. Similarly, given a certain C  = 90%, porous
                                                                                                 2
            constant design parameters of  C  = 90% and  ε = 0.47   biomaterials in sub-region A have a constant  C  value
                                                                                                       face
                                       2
            (No. 09, 13, 14, and 15) ranges from 38.55 to 190.19 MPa   equal to 90% and a variable C  value ranging between 60%
                                                                                      cell
            Volume 9 Issue 6 (2023)                         50                        https://doi.org/10.36922/ijb.0222
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