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Gene & Protein in Disease                      DNA methylation and gene expression on rats with protein malnutrition




























            Figure 11. The species and its sequenced samples were classified and counted for variable shear events.

            Table 10. Variable shear type statistics.

             AS_      LPE_1  LPE_2   LPE_3  LPE_4  LPF_1  LPF_2   LPF_3  LPF_4  CON_1   CON_2   CON_3  CON_4
             category
            AE         756    815     620    770    571    744     743    756    775     677     768     916
                      (2.33)  (2.37)  (2.14)  (2.36)  (2.09)  (2.30)  (2.28)  (2.28)  (2.30)  (2.20)  (2.35)  (2.42)
            IR         290    344     222    298    202    286     318    294    312     264     292     398
                      (0.89)  (1.00)  (0.77)  (0.91)  (0.74)  (0.88)  (0.97)  (0.89)  (0.92)  (0.86)  (0.89)  (1.05)
            MIR        24      30     12     24     14      20     28     28      26      24     24      28
                      (0.07)  (0.09)  (0.04)  (0.07)  (0.05)  (0.06)  (0.09)  (0.08)  (0.08)  (0.08)  (0.07)  (0.07)
            MSKIP      367    397     297    370    264    345     371    345    369     319     355     511
                      (1.13)  (1.15)  (1.02)  (1.14)  (0.97)  (1.07)  (1.14)  (1.04)  (1.09)  (1.04)  (1.09)  (1.35)
            SKIP      2072    2292   1522   2044    1410   1978   2054   2042    2208    1754    2058   2776
                      (6.37)  (6.66)  (5.25)  (6.27)  (5.17)  (6.11)  (6.29)  (6.17)  (6.54)  (5.71)  (6.31)  (7.35)
            TSS       14,550   15,358   13,170   14,593   12,426   14,519   14,645   14,894   15,098   13,898   14,625   16,676
                      (44.76)  (44.61)  (45.45)  (44.80)  (45.55)  (44.88)  (44.85)  (44.97)  (44.72)  (45.21)  (44.82)  (44.12)
            TTS       13,664   14,368   12,526   13,703   11,814   13,651   13,736   13,967   14,146   13,113   13,719   15,448
                      (42.04)  (41.74)  (43.23)  (42.06)  (43.31)  (42.19)  (42.07)  (42.17)  (41.90)  (42.65)  (42.04)  (40.87)
            XAE        131    143     116    148    106    169     137    144    152     146     141     199
                      (0.40)  (0.42)  (0.40)  (0.45)  (0.39)  (0.52)  (0.42)  (0.43)  (0.45)  (0.47)  (0.43)  (0.53)
            XIR        92     109     67     81     62      89     87     101     98      78     85      113
                      (0.28)  (0.32)  (0.23)  (0.25)  (0.23)  (0.28)  (0.27)  (0.30)  (0.29)  (0.25)  (0.26)  (0.30)
            XMIR        4      6      2       6      4      4      6       6      6       8       4       6
                      (0.01)  (0.02)  (0.01)  (0.02)  (0.01)  (0.01)  (0.02)  (0.02)  (0.02)  (0.03)  (0.01)  (0.02)
            XMSKIP     117    107     94     111    84      94     110    106    112      97     111     139
                      (0.36)  (0.31)  (0.32)  (0.34)  (0.31)  (0.29)  (0.34)  (0.32)  (0.33)  (0.32)  (0.34)  (0.37)
            XSKIP      438    457     330    428    321    455     415    434    459     366     449     584
                      (1.35)  (1.33)  (1.14)  (1.31)  (1.18)  (1.41)  (1.27)  (1.31)  (1.36)  (1.19)  (1.38)  (1.55)
            LPE: Early-life low-protein group, LPF: Fetal low-protein group, CON: Control group

            restriction and subsequently chronic diseases at genetic   the upregulated or downregulated differentially expressed
            level. The changes in gene expression profile detected by   genes from tens of thousands of genes and then search
            high-throughput sequencing technology are based on the   for the candidate gene groups from the key differentially
                                                                            [28]
            changes in mRNA transcription level, which can screen for   expressed genes . This study compared the whole gene


            Volume 1 Issue 2 (2022)                         14                     https://doi.org/10.36922/gpd.v1i2.169
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