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Gene & Protein in Disease DNA methylation and gene expression on rats with protein malnutrition

A

B

C

Figure 13. (A-C) Analysis of chromosome methylation levels.

pathway, cell metabolism, immune response, and other regulation. Differentially expressed genes in the LPE
processes. The differentially expressed genes in the LPF versus CON group mainly involved signaling molecule
versus LPE group were mainly related to endocrine interaction, immune system, amino acid metabolism,
metabolism, cell division and stress response, and their and cofactor metabolism pathways . The differentially
[38]
molecular functions were mainly ATP binding, protein expressed genes in the LPF versus LPE group were
kinase activity, and heme binding. According to KEGG mainly involved in the regulation of immune system,
enrichment results, the differentially expressed genes in cytokine signal regulation, tissue system, endocrine and
the LPE versus CON group were mainly involved in viral metabolic diseases, lipid metabolism, energy metabolism,
infection, lipid metabolism regulation, signaling pathway and cofactor metabolism. Therefore, malnutrition in
regulation of various factors, and nervous system early life can affect a number of biological functions

Volume 1 Issue 2 (2022) 16 https://doi.org/10.36922/gpd.v1i2.169